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D-Galactose

D-Galactose  Structure
CAS No.
59-23-4
Chemical Name:
D-Galactose
Synonyms
Gal;a-D-Galactopyranose;actose;galactos;(2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal;%Cerebrose;d-galactos;D-galatose;brain sugar
CBNumber:
CB1327034
Molecular Formula:
C6H12O6
Molecular Weight:
180.16
MOL File:
59-23-4.mol
MSDS File:
SDS
Modify Date:
2024/7/1 14:39:02

D-Galactose Properties

Melting point 168-170 °C(lit.)
alpha +79.0~+81.0°(D/20℃) (c=10, dil. NH4OH)
Boiling point 232.96°C (rough estimate)
Density 1,5 g/cm3
refractive index 80 ° (C=10, H2O)
storage temp. room temp
solubility H2O: 100 mg/mL
form powder
pka pK1:12.35 (25°C)
color White
Odor Odorless
PH Range 5 - 7 at 180 g/l at 25 °C
PH 4.5-6.0 (H2O)Aqueous solution
optical activity [α]20/D +80±1°, 24 hr, c = 5% in H2O
Water Solubility Soluble in water.
Merck 14,4335
BRN 1724619
InChIKey GZCGUPFRVQAUEE-DPYQTVNSSA-N
LogP -2.490 (est)
CAS DataBase Reference 59-23-4(CAS DataBase Reference)
NIST Chemistry Reference D-Galactose(59-23-4)
EPA Substance Registry System D-Galactose (59-23-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-27-26
WGK Germany  3
RTECS  LW5490000
3
TSCA  Yes
HS Code  29400090
NFPA 704
0
1 0

D-Galactose price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G6404 D-(+)-Galactose BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99% 59-23-4 10G ₹5693.95 2022-06-14 Buy
Sigma-Aldrich(India) PHR1206 Galactose Pharmaceutical Secondary Standard; Certified Reference Material 59-23-4 500MG ₹8508.45 2022-06-14 Buy
Sigma-Aldrich(India) G6404 D-(+)-Galactose BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99% 59-23-4 25G ₹8562.58 2022-06-14 Buy
Sigma-Aldrich(India) G0750 D-(+)-Galactose ≥99% 59-23-4 10MG ₹1818.6 2022-06-14 Buy
Sigma-Aldrich(India) G6404 D-(+)-Galactose BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99% 59-23-4 100G ₹23100.55 2022-06-14 Buy
Product number Packaging Price Buy
G6404 10G ₹5693.95 Buy
PHR1206 500MG ₹8508.45 Buy
G6404 25G ₹8562.58 Buy
G0750 10MG ₹1818.6 Buy
G6404 100G ₹23100.55 Buy

D-Galactose Chemical Properties,Uses,Production

Description

D-Galactose is a monosaccharide sugar that serves as an energy source and glycosylation component. It is a C-4 epimer of glucose and often used as a source of carbon in culture media. Galactose is a component of the disaccharide lactose and released upon hydrolysis by β-galactosidase enzymes. It is converted to glucose via the Leloir pathway or metabolized via an alternative pathway, such as the DeLey-Doudoroff pathway.

Chemical Properties

White powder

Uses

D-Galactose is suitable for use in cell culture systems requiring sugar additives.

Application

Galactose has been used:
as a component of galactosyltransferase labeling buffer.
as a supplement in MRS broth for the growth of thermophilic lactobacilli.
to induce the expression of uncoupling protein (UCP) in yeast transformants.

Definition

A monosaccharide commonly occurring in milk sugar or lactose.

General Description

Galactose is a constituent of lactose. It is one of the main nutrients for newborn infants and young children. It is produced in the body for the formation of lactose and is also a component of glycolipids (cerebrosides) and glycoproteins.

Biological Activity

Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.

Purification Methods

D-Galactose is crystallised twice from aqueous 80% EtOH at -10o, then dried in a vacuum oven at 90o over P2O5 for 10hours. [Link Biochemical Preparations 3 75 1953, Hansen et al. Biochemical Preparations 4 2 1955.] Also purify it by recrystallising the dried solid (150g) in hot H2O (150mL), then adding hot MeOH (250mL) and hot EtOH (500mL), stirring to mix, filtering through a bed of charcoal, and the clear filtrate is stirred to initiate crystallisation. After standing overnight at 10o, the crystals of the -anomer are filtered off by suction, washed with MeOH, then EtOH, and dried (yield 130g), and more can be obtained by evaporation of the filtrate and washing as before. [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 120 1962, Academic Press, Beilstein 1 IV 4336.]

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