Hyperoside
- CAS No.
- 482-36-0
- Chemical Name:
- Hyperoside
- Synonyms
- HYPERIN;QUERCETIN-3-O-GALACTOSIDE;quercetin 3-O-β-D-galactopyranoside;QUERCETIN-3-GALACTOSIDE;QUERCETIN-3-D-GALACTOSIDE;HYPEROSID;actoside;hyperasid;HYPEROSIDE;hyperozide
- CBNumber:
- CB9240043
- Molecular Formula:
- C21H20O12
- Molecular Weight:
- 464.38
- MOL File:
- 482-36-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/10 22:07:33
| Melting point | 225-226°C |
|---|---|
| Boiling point | 872.6±65.0 °C(Predicted) |
| Density | 1.87±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 6.17±0.40(Predicted) |
| color | Light Yellow to Yellow |
| BRN | 5784795 |
| LogP | -0.111 (est) |
| CAS DataBase Reference | 482-36-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-40 | |||||||||
| Safety Statements | 22-45-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DJ3009200 | |||||||||
| F | 10-23 | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
Hyperoside price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 83388 | Quercetin 3-D-galactoside ≥97.0% (HPLC) | 482-36-0 | 1MG | ₹8432.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2691 | Hyperoside Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 100?mg | 482-36-0 | 100MG | ₹79758.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 83388 | Quercetin 3-D-galactoside ≥97.0% (HPLC) | 482-36-0 | 5MG | ₹25752.68 | 2022-06-14 | Buy |
Hyperoside Chemical Properties,Uses,Production
Description
Hypericin, which is widely found in various plants, such as Hypericum, Rosaceae, Campanulaceae, Labiatae, Rhododendron, Asteraceae Kwai, Garciniaceae, Leguminosae, Euonymus, and other fruits and whole grass, is a flavonoid compound.
Chemical Properties
Yellow Solid
Physical properties
Appearance: yellowish needlelike crystals. Melting point: 227–229 °C. Specific optical rotation: ?83° (c = 0.2, pyridine). Solubility: soluble in ethanol, methanol, acetone, and pyridine. Hydrochloric acid–magnesium powder reaction yielded formation of cherry red; ferric chloride reaction was green; α-naphthol reaction was positive.
History
In 1960, Nair et al. isolated hyperin from redosier dogwood, in which its content is 0.075%. Flavonoids in the treatment of cardiovascular and cerebrovascular diseases play a pivotal role, among which rutin is a typical representative. Isoquetin mainly presents in the leaves of kumquat flowers and the oleander plant kenaf, and it can also be obtained by chemical synthesis. It shows an anti-inflammatory effect through the capillary permeability test and other animal experiments. It also has a toxic effect on the larvae of Chilohabala larvae. It is one of the active ingredients of Hypericum japonicum, which is used in the treatment of hepatitis because of its inhibition of the activities of hepatic enzyme.
Uses
Hyperoside is used as a primary reference standard in the analysis of herbal medicinal products. It may be used as a calibration standard in method validation of polyphenols from leaf extracts using HPLC method.
Indications
This product is available in the British Pharmacopoeia (2017) and the European
Pharmacopoeia (9.0th ed.).
Monomeric compounds are currently used clinically. In clinical practice, hypericin
is the main active ingredient of proprietary Chinese medicines, such as
Acanthopanax capsules, of which Acanthopanax stem and leaf extract are the raw
materials for the preparation. Xin’an capsules, prepared with hawthorn leaf extract,
are rich in flavonoids, in which hyperoside, a kind of flavonoid, is one of the main
components. Qi yue lipid-lowering tablets are prepared from the effective parts of
Chinese medicinal herbs such as hawthorn (Nucleation) and Astragalus membranaceus.
Flavonoid is one of the main active ingredients in hawthorn, in which hyperoside
content is higher. Xinxuening tablets, containing ursolic acid, vitexin
rhamnoside, hyperoside, citric acid, and others, is a preparation made from hawthorn
and pueraria and other traditional Chinese medicines, in which hawthorn
enhances the actions of the medicine. Clinical indications of Xinxuening tablets are
coronary heart disease, angina pectoris, chest tightness, palpitations, high blood
pressure, arrhythmia, hyperlipidemia, and mental depression.
Definition
ChEBI: A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity.
General Description
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Hyperoside Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12458 | 58 | Inquiry |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +86-86177 | China | 2901 | 58 | Inquiry |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | China | 871 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
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