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Taxifolin

Taxifolin Structure
CAS No.
480-18-2
Chemical Name:
Taxifolin
Synonyms
DIHYDROQUERCETIN;distylin;taxifoliol;Larch extract;(+)-TAXIFOLIN;(2R,3R)-(+)-Taxifolin;(2R,3R)-DIHYDROQUERCETIN;Taxifolin (Dihydroquercetin);CPD-474;Lavitol
CBNumber:
CB0402424
Molecular Formula:
C15H12O7
Molecular Weight:
304.25
MOL File:
480-18-2.mol
Modify Date:
2024/6/14 12:24:17

Taxifolin Properties

Melting point 230-233°C (dec.)
Boiling point 365.09°C (rough estimate)
Density 1.3326 (rough estimate)
refractive index 1.4790 (estimate)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 7.39±0.60(Predicted)
color White to Yellow
BRN 5299277
InChI InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
InChIKey CXQWRCVTCMQVQX-LSDHHAIUSA-N
SMILES [C@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP 0.950
CAS DataBase Reference 480-18-2(CAS DataBase Reference)
EPA Substance Registry System 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- (480-18-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  LK6920000
HazardClass  IRRITANT
HS Code  29329990
NFPA 704
0
2 0

Taxifolin price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 78666 Taxifolin analytical standard 480-18-2 25MG ₹9645.08 2022-06-14 Buy
Sigma-Aldrich(India) 78666 Taxifolin analytical standard 480-18-2 100MG ₹23620.15 2022-06-14 Buy
TCI Chemicals (India) T3666 (+)-Taxifolin 480-18-2 200MG ₹3000 2022-05-26 Buy
TCI Chemicals (India) T3666 (+)-Taxifolin 480-18-2 1G ₹8400 2022-05-26 Buy
ottokemi T 1252 Taxifolin 98%+ 480-18-2 10mg ₹3609 2022-05-26 Buy
Product number Packaging Price Buy
78666 25MG ₹9645.08 Buy
78666 100MG ₹23620.15 Buy
T3666 200MG ₹3000 Buy
T3666 1G ₹8400 Buy
T 1252 10mg ₹3609 Buy

Taxifolin Chemical Properties,Uses,Production

Description

Taxifolin, a chemical substance extracted from pine plants such as larch and Douglas fir. It belongs to the bioflavonoid pseudo-vitamin P, and its scientific name is dihydroquercetin. Japanese scholar Fukui first isolated it from the leaves of conifers (Chamaecyparis obtusa), and its biological activity was subsequently discovered and confirmed.

Chemical Properties

Yellow Solid

Uses

An antioxidant flavenoid.

Definition

ChEBI: A taxifolin that has (2R,3R)-configuration.

Application

Taxifolin is a flavonoid commonly found in onion, milk, French maritime pine bark and Douglas fir bark. It is also used in various commercial preparations like Legalon?, Pycnogenol?, and Venoruton?. This review focuses on taxifolin’s biological activities and related molecular mechanisms. It showed promising pharmacological activities in the management of inflammation, tumors, microbial infections, oxidative stress, cardiovascular, and liver disorders. The anti-cancer activity was more prominent than other activities evaluated using different in vitro and in vivo models. Further research on the pharmacokinetics, in-depth molecular mechanisms, and safety profile using well-designed randomized clinical studies are suggested to develop a drug for human use.

General Description

Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.

Taxifolin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 426)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Wuhan Haorong Biotechnology Co.,ltd +8618565342920 China 270 58 Inquiry
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Hebei Kingfiner Technology Development Co.Ltd +86-15532196582 +86-15373005021 China 2990 58 Inquiry

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Taxifolin Spectrum

2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on( 2,3-dihydro-3,3’,4’,5,7-pentahydroxy-flavon 2theta-trans)- 3,3’,4’,5,7-pentahydroxy-flavanon dihydro-querceti TAXIFOLIN(P) TAXIFOLIN, (+)-(RG) (2R-trans)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyrone Dihydroquercetin,~99% TAXIFOLIN SNAP-N-SHOOT 0.1mg/mL(P) (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (+)-Taxifolin ,98% (+)-trans Taxifolin 2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)- 2-(3,4,5-Trihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-4H-1-benzopyran-4-one (3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro taxifolin or dihydroquercetin CPD-474 trans dihydroquercetin (2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone (2R,3R)-Dihydroquercetin (2R,3R)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-1-benzopyran-4-one Diquertin Lariksin Lavitol (+)-3,3',4',5,7-PENTAHYDROXYFLAVANONE 3,3',4',5,7-PENTAHYDROXYFLAVANONE (2R,3R)-3,3',4',5,7-PENTAHYDROXYFLAVANONE 3,5,7,3',4'-PENTAHYDROXYFLAVANONE (+)-DIHYDROQUERCETIN TAXIFOLIN TAXIFOLIN, (+)- Taxifoliol,Distylin 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroMan-4-one Taxifolin SynonyMs (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- (2S,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-chromanone 3,3',4',5,7-Pentahydroxydihydroflavone 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R-trans)- FLAVANONE, 3,3',4',5',7-PENTAHYDROXY (2R,3R)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxo-3,4-dihydro-2H-1-benzopyran-5-olate Taxifolin,TAX Taxifolin USP/EP/BP (+)-(2R,3R)-Dihydroquercetin (+)-Dihydroquercetin Dihydroquercetin/Taxifolin (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one distylin (2R,3R)-(+)-Taxifolin DIHYDROQUERCETIN Taxifolin (Dihydroquercetin) Larch extract (2R,3R)-DIHYDROQUERCETIN (+)-TAXIFOLIN taxifoliol (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one