Pinostrobin
- CAS No.
- 480-37-5
- Chemical Name:
- Pinostrobin
- Synonyms
- Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
- CBNumber:
- CB7350900
- Molecular Formula:
- C16H14O4
- Molecular Weight:
- 270.28
- MOL File:
- 480-37-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 100°C |
|---|---|
| Boiling point | 494.9±45.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml |
| form | A crystalline solid |
| pka | 7.40±0.40(Predicted) |
| color | White to yellow |
| LogP | 3.591 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Pinostrobin Chemical Properties,Uses,Production
Description
Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).
Definition
ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.
Pinostrobin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 122)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| chromsynth pvt ltd | +919704220374 | Hyderabad, India | 244 | 58 | Inquiry |
| Biosyn Research Chemicals | +91 9346022300/+91 9399339999 | Telangana, India | 1340 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 | China | 952 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 12330 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
480-37-5(Pinostrobin)Related Search:
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2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one
Pinostobin
Pistrobin
Pinostrobin,(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL)
5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one
5-Hydroxy-7-methoxyflavanone
(S)-2,3-DIHYDRO-5-HYDROXY-7-METHOXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE
PINOSTROBIN
(S)-2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone
(2S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)-
Pinostrombin
5-Hydroxy-7-methoxyflavanone (Pinostrobin)
5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
loteprednol Impurity 18
480-37-5
Food Residue Analysis
Food & Beverage Standards
Chromatography
Analytical Standards
Analytical Chromatography Product Catalog
Flavanones