Pterostilbene
- CAS No.
- 537-42-8
- Chemical Name:
- Pterostilbene
- Synonyms
- pterostibene;hydroxystilbene;AKOS 236-80;PTEROSTILBENE;(Z)-3,4’-aminostilbene;(E/Z)-3,4’POVIDONE USP(RG);Pterostilbene>PTEROSTILBENE(FG)
- CBNumber:
- CB8373368
- Molecular Formula:
- C16H16O3
- Molecular Weight:
- 256.3
- MOL File:
- 537-42-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/28 14:37:56
| Melting point | 89-92 ºC |
|---|---|
| Boiling point | 420.4±35.0 °C(Predicted) |
| Density | 1.169±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >20mg/mL |
| pka | 9.96±0.26(Predicted) |
| form | solid |
| color | White or off-white |
| Odor | Characteristic |
| λmax | 321nm(MeOH)(lit.) |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week. |
| InChI | InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+ |
| InChIKey | VLEUZFDZJKSGMX-ONEGZZNKSA-N |
| SMILES | C1(O)=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2)C=C1 |
| LogP | 4.056 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318-H411 | |||||||||
| Precautionary statements | P273-P280-P305+P351+P338-P391-P501 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 41-51/53 | |||||||||
| Safety Statements | 26-39-61 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29095000 | |||||||||
| NFPA 704 |
|
Pterostilbene price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P1499 | Pterostilbene ≥97% (HPLC), solid | 537-42-8 | 10MG | ₹29887.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 523310 | Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties. | 537-42-8 | 10MG | ₹23839.99 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P1924 | Pterostilbene | 537-42-8 | 100MG | ₹14400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P1924 | Pterostilbene | 537-42-8 | 1G | ₹28400 | 2022-05-26 | Buy |
| ottokemi | P 5969 | Pterostilbene 99% | 537-42-8 | 10mg | ₹24003 | 2022-05-26 | Buy |
Pterostilbene Chemical Properties,Uses,Production
Description
Pterostilbene (PTS) is a fragrant-smelling hydrocarbon called "styrene", which is a derivative of resveratrol. It is found in blueberries and Pterocarpus marsupium (PM) heartwood. Similar to resveratrol, PTS has anti-inflammatory, anti-thrombotic, anti-cancer, anti-cancer, anti-hyperlipidemia and antibacterial effects.
Chemical Properties
Pterostilbene is a white crystalline powder, sensitive to air, soluble in hot methanol, DMSO, insoluble in water. It is a stilbenoid chemically similar to resveratrol and from the leguminous plant Pterocarpus indicus.
Occurrence
Pterostilbene is a natural molecule found in fruits, vegetables and nuts. Blueberries are often quoted as one of the richest sources of pterostilbene. It is also found in almonds,various Vaccinium berries (including blueberries), grape leaves and vines,and Pterocarpus marsupium heartwood.
Uses
Substantial studies demonstrate that pterostilbene has diverse pharmacological activities for the prevention and treatment of diseases including inflammation, cancer, diabetes, and dyslipidemia.
Pterostilbene has been used:
to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
Definition
ChEBI: Pterostilbene is a stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. It has a role as an antioxidant, an antineoplastic agent, a neurotransmitter, a plant metabolite, an apoptosis inducer, a neuroprotective agent, an anti-inflammatory agent, a radical scavenger and a hypoglycemic agent. It is a stilbenol, a member of methoxybenzenes and a diether. It derives from a hydride of a trans-stilbene.
Preparation
Pterostilbene was synthesized from 3,5-dimethoxybenzyl bromide and p-nitrobenzaldehyde by Witting-Hornor reaction, reduction, diazotization and hydrolysis, with a total yield of 53.9%.
benefits
Pterostilbene is a naturally-derived stilbenoid structurally related to resveratrol, with potential antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic and cytoprotective activities. Pterostilbene is known to have many pharmacological benefits for the prevention and treatment of a wide variety of diseases, including ( cancer (McCormack and McFadden 2012), dyslipidaemia (Rimando et al. 2005), diabetes (Amarnath Satheesh and Pari 2006), cardiovascular degeneration (Amarnath Satheesh and Pari 2008) and pain (Hougee et al. 2005).
Side effects
The side effects of pterostilbene are relatively minor, but you still need to pay attention to the dosage. Low-dose pterostilbene supplementation improves cholesterol metabolism and reduces triglyceride levels. Side effects include mild weight loss and muscle pain, but dose adjustment is usually not necessary.
Pterostilbene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Clavita Pharma Pvt Ltd | +91-4023750123 +91-4023750123 | Hyderabad, India | 5 | 58 | Inquiry |
| Laurus Labs Ltd | +91-4066594333 +91-4039804333 | Telangana, India | 50 | 58 | Inquiry |
| Chemical Resources | +91-1725022460 +91-1725022460 | Haryana, India | 17 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Biosyn Research Chemicals | +91 9346022300/+91 9399339999 | Telangana, India | 1340 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Biomax Life Sciences Limited | 08008706071 | Hyderabad, India | 5 | 58 | Inquiry |
| Vxl Life Sciences | 08048371846Ext 158 | Mumbai, India | 9 | 58 | Inquiry |
| Lifecare Laboratories Pvt Ltd (Formerly Transglobe & Sai Ram Organics Pvt. Ltd) | 91-40-23750123 | Hyderabad, India | 3 | 58 | Inquiry |
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Related Qustion
- Q:Is pterostilbene better than resveratrol?
- A:Pterostilbene exhibits increased bioavailability due to the presence of two methoxy groups, which cause it to exhibit increase....
- Jan 15，2024