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Nitrefazole

Nitrefazole Structure
CAS No.
21721-92-6
Chemical Name:
Nitrefazole
Synonyms
bt-985;ALTIMOL;EMD 15700;NITREFAZOLE;1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE;2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol;2-methyl-4-nitro-1-(4-nitrophenyl)imidazole;2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol;2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole;1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
CBNumber:
CB3356045
Molecular Formula:
C10H8N4O4
Molecular Weight:
248.19
MOL File:
21721-92-6.mol
Modify Date:
2023/5/4 17:34:35
Request For Quotation

Nitrefazole Properties

Melting point 185-187°
storage temp. Refrigerator
solubility Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
color Light Yellow to Yellow

Nitrefazole Chemical Properties,Uses,Production

Description

Nitrefazole is an inhibitor of aldehyde dehydrogenase useful in the management of alcoholism. Cited advantages over disulfiram include longer duration of action, higher specificity (no inhibition of dopamine β-hydroxylase) and fewer side effects. It is generally recognized that the efficacy of such agents with respect to permanent abstinence is low. However, temporary abstinence and/or controlled drinking may facilitate supportive psychotherapy and/or delay the onset of severe alcoholic diseases.

Uses

Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.

World Health Organization (WHO)

Nitrefazole, which is used in the treatment of alcoholism, was introduced in the early 1980s. By 1984 its use had been associated with hepatotoxic reactions, some of which were fatal. This led to its withdrawal in at least two countries. WHO has no information to suggest that preparations containing nitrefazole remain commercially available.

Nitrefazole Preparation Products And Raw materials

Raw materials

Preparation Products

Nitrefazole Suppliers

Global( 12)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Dongyang Qiusuo Medical Technology Co., LTD 17502510579 China 1558 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 China 5534 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Dongyang Qiusuo Medical Technology Co., LTD 58
TargetMol Chemicals Inc. 58
EMD Biosciences, Inc. 66
CHEMICAL LAND21 74
3B Scientific Corporation 47
Lanospharma Laboratories Co.,Ltd 56
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Energy Chemical 58

21721-92-6(Nitrefazole)Related Search:

Miconazole nitrate cream 2-Methyl-4-nitroimidazole 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE 1-(4-Nitrophenyl)-1H-imidazole Nitrefazole
4-(2-METHYLIMIDAZOL-1-YL)PHENYLAMINE 1,2-DIMETHYL-4-NITRO-1H-IMIDAZOLE 4-NITRO-1-PHENYLIMIDAZOLE
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ALTIMOL 1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE EMD 15700 2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol 2-methyl-4-nitro-1-(4-nitrophenyl)imidazole 2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol bt-985 NITREFAZOLE 2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole 1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)- 21721-92-6 C10H8N4O4