(-)-8-PHENYLMENTHOL
- CAS No.
- 65253-04-5
- Chemical Name:
- (-)-8-PHENYLMENTHOL
- Synonyms
- (-)-PHENMENTHOL;(-)-8-PHENYLMENTHOL;(-)-8-PHENYLMENTHOL;(-)-8-Phenylmenthol,97%;(-)-8-Phenylmenthol,98%;(-)-8-Phenylmenthol 98%;(-)-8-Phenylmenthol, GC 97%;(1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexanol;(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol;5-METHYL-2-(1-METHYL-1-PHENYLETHYL)-(1R,2S,5R)-CYCLOHEXANOL
- CBNumber:
- CB3443505
- Molecular Formula:
- C16H24O
- Molecular Weight:
- 232.36
- MOL File:
- 65253-04-5.mol
- Modify Date:
- 2023/4/23 13:52:06
alpha | -26°(20/D, c=2, C2H5OH) |
---|---|
Boiling point | 130 °C (0.7501 mmHg) |
Density | 0.999 g/mL at 20 °C (lit.) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | Sealed in dry,2-8°C |
solubility | Chloroform (Slightly), Methanol (Very Slightly) |
pka | 15.21±0.60(Predicted) |
form | Viscous Liquid |
color | Clear colorless to light yellow |
Specific Gravity | 0.999 |
optical activity | [α]20/D 26°, c = 2 in ethanol |
λmax | 259nm(CH2Cl2)(lit.) |
BRN | 3651167 |
CAS DataBase Reference | 65253-04-5(CAS DataBase Reference) |
(-)-8-PHENYLMENTHOL Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS OILY LIQUID
Uses
(-)-8-Phenylmenthol is used to prepare piperidine-based analogs of cocaine as monoamine reuptake inhibitors. It is also used to prepare quinuclidinyl (fluoroalkyl)benzilate as muscarinic receptor antagonist.
Purification Methods
Dissolve the menthol in toluene, dry (Na2SO4), evaporate and chromatograph it on a silica gel column and eluting with 5% Et2O in pet ether to give an oil with the desired rotation. IR has max 3420cm-1 (OH) with consistent 1H NMR [Corey & Ensley J Org Chem 43 1610 1978, Whitesell et al. Tetrahedron 42 2993 1986, Bednarski & Danishefsky J Am Chem Soc 108 7060 1986].
(-)-8-PHENYLMENTHOL Preparation Products And Raw materials
Raw materials
Preparation Products
(-)-8-PHENYLMENTHOL Suppliers
Global( 65)Suppliers
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Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 41844 | 58 | Inquiry |
Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 | China | 54986 | 58 | Inquiry |
65253-04-5((-)-8-PHENYLMENTHOL)Related Search:
(-)-PHENMENTHOL
(-)-8-PHENYLMENTHOL
Cyclohexanol, 5-methyl-2-(1-methyl-1-phenylethyl)-, (1R,2S,5R)-
(-)-8-Phenylmenthol, GC 97%
5-METHYL-2-(1-METHYL-1-PHENYLETHYL)-(1R,2S,5R)-CYCLOHEXANOL
(-)-8-Phenylmenthol,98%
(-)-8-Phenylmenthol,97%
(1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexanol
(-)-8-Phenylmenthol 98%
(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol
(-)-8-PHENYLMENTHOL
65253-04-5
Asymmetric Synthesis
Chiral Building Blocks
Alcohols
Organic Building Blocks