(-)-8-PHENYLMENTHOL

(-)-8-PHENYLMENTHOL Structure
CAS No.
65253-04-5
Chemical Name:
(-)-8-PHENYLMENTHOL
Synonyms
(-)-PHENMENTHOL;(-)-8-PHENYLMENTHOL;(-)-8-PHENYLMENTHOL;(-)-8-Phenylmenthol,97%;(-)-8-Phenylmenthol,98%;(-)-8-Phenylmenthol 98%;(-)-8-Phenylmenthol, GC 97%;(1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexanol;(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol;5-METHYL-2-(1-METHYL-1-PHENYLETHYL)-(1R,2S,5R)-CYCLOHEXANOL
CBNumber:
CB3443505
Molecular Formula:
C16H24O
Molecular Weight:
232.36
MOL File:
65253-04-5.mol
Modify Date:
2023/4/23 13:52:06

(-)-8-PHENYLMENTHOL Properties

alpha -26°(20/D, c=2, C2H5OH)
Boiling point 130 °C (0.7501 mmHg)
Density 0.999 g/mL at 20 °C (lit.)
refractive index n20/D 1.53(lit.)
Flash point >230 °F
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Methanol (Very Slightly)
pka 15.21±0.60(Predicted)
form Viscous Liquid
color Clear colorless to light yellow
Specific Gravity 0.999
optical activity [α]20/D 26°, c = 2 in ethanol
λmax 259nm(CH2Cl2)(lit.)
BRN 3651167
CAS DataBase Reference 65253-04-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
3-8-10
HS Code  29061900

(-)-8-PHENYLMENTHOL Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS OILY LIQUID

Uses

(-)-8-Phenylmenthol is used to prepare piperidine-based analogs of cocaine as monoamine reuptake inhibitors. It is also used to prepare quinuclidinyl (fluoroalkyl)benzilate as muscarinic receptor antagonist.

Purification Methods

Dissolve the menthol in toluene, dry (Na2SO4), evaporate and chromatograph it on a silica gel column and eluting with 5% Et2O in pet ether to give an oil with the desired rotation. IR has max 3420cm-1 (OH) with consistent 1H NMR [Corey & Ensley J Org Chem 43 1610 1978, Whitesell et al. Tetrahedron 42 2993 1986, Bednarski & Danishefsky J Am Chem Soc 108 7060 1986].

(-)-8-PHENYLMENTHOL Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-8-PHENYLMENTHOL Suppliers

Global( 65)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Qingdao Dexin Chemical Co., Ltd +86-15553333686 +86-15553333686 China 2865 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 China 41844 58 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 4008210725 4008210725 China 54986 58 Inquiry
(-)-PHENMENTHOL (-)-8-PHENYLMENTHOL Cyclohexanol, 5-methyl-2-(1-methyl-1-phenylethyl)-, (1R,2S,5R)- (-)-8-Phenylmenthol, GC 97% 5-METHYL-2-(1-METHYL-1-PHENYLETHYL)-(1R,2S,5R)-CYCLOHEXANOL (-)-8-Phenylmenthol,98% (-)-8-Phenylmenthol,97% (1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexanol (-)-8-Phenylmenthol 98% (1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol (-)-8-PHENYLMENTHOL 65253-04-5 Asymmetric Synthesis Chiral Building Blocks Alcohols Organic Building Blocks