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1-(5-Chloro-2-hydroxyphenyl)ethanone

1-(5-Chloro-2-hydroxyphenyl)ethanone Structure
CAS No.
1450-74-4
Chemical Name:
1-(5-Chloro-2-hydroxyphenyl)ethanone
Synonyms
1-(5-CHLORO-2-HYDROXYPHENYL)ETHAN-1-ONE;5-CHLORO-2-HYDROXYACETOPHENONE;1-(3-chlorophenyl)-2-hydroxyethan-1-one;AKOS BB-6937;ASISCHEM D38764;SALOR-INT L497495-1EA;2-Acetyl-4-chlorophenol;oro-2'-hydroxyacetophenone;2'-hydroxy-5'-chlorophenone;2-HYDROXY-5-CHLORO ACETOPHENONE
CBNumber:
CB3482191
Molecular Formula:
C8H7ClO2
Molecular Weight:
170.59
MOL File:
1450-74-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:06

1-(5-Chloro-2-hydroxyphenyl)ethanone Properties

Melting point 54-56 °C(lit.)
Boiling point 126-128 °C28 mm Hg(lit.)
Density 1.2315 (rough estimate)
refractive index 1.5590 (estimate)
Flash point 107-109°C/12mm
storage temp. Sealed in dry,Room Temperature
form Solid
pka 9.72±0.18(Predicted)
BRN 1365589
InChIKey XTGCUDZCCIRWHL-UHFFFAOYSA-N
CAS DataBase Reference 1450-74-4(CAS DataBase Reference)
NIST Chemistry Reference Ethanone, 1-(5-chloro-2-hydroxyphenyl)-(1450-74-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
Hazard Note  Irritant
HS Code  29147000
NFPA 704
1
2 0

1-(5-Chloro-2-hydroxyphenyl)ethanone price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 383384 5′-Chloro-2′-hydroxyacetophenone 99% 1450-74-4 5G ₹2608.83 2022-06-14 Buy
Sigma-Aldrich(India) 383384 5′-Chloro-2′-hydroxyacetophenone 99% 1450-74-4 25G ₹8833.2 2022-06-14 Buy
ALFA India ALF-A15448-06 5'-Chloro-2'-hydroxyacetophenone, 99% 1450-74-4 5g ₹2048 2022-05-26 Buy
ALFA India ALF-A15448-03 5'-Chloro-2'-hydroxyacetophenone, 99% 1450-74-4 1g ₹522 2022-05-26 Buy
ottokemi C 6521 5′-Chloro-2′-hydroxyacetophenone, 99% 1450-74-4 5gm ₹2601 2022-05-26 Buy
Product number Packaging Price Buy
383384 5G ₹2608.83 Buy
383384 25G ₹8833.2 Buy
ALF-A15448-06 5g ₹2048 Buy
ALF-A15448-03 1g ₹522 Buy
C 6521 5gm ₹2601 Buy

1-(5-Chloro-2-hydroxyphenyl)ethanone Chemical Properties,Uses,Production

Chemical Properties

slightly yellow crystalline powder or chunks

Uses

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) may be used in the synthesis of:

  • 6-chloro-2-methyl-4H-chrome-4-one
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 2-styrenyl allyl ether

Preparation

Preparation by Fries rearrangement of 4-chlorophenyl acetate with aluminium chloride without solvent between 110° and 200°(90–100% yield).

General Description

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) on condensation with salicylhydrazide yields Schiff base, which is reported to form copper(II) complexes. Dipole moment of 5-chloro-2- hydroxyacetophenone has been evaluated in benzene solution.

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5'-Chloro-2'-Hydroxy Acetophenone 2'-Hydorxy-5'-Chloro Acetophenone 2'-Hydorxy-5'-ChloroAcetophenone Acetophenone, 5'-chloro-2'-hydroxy- Acetophenone,5-chloro-2-hydroxy- 5'-Chloro-2'-hydroxyacetophenone,99% Ethanone,1-(5-chloro-2-hydroxyphenyl)- ASISCHEM D38764 2'-HYDROXY-5'-CHLORO ACETOPHENONE 2-HYDROXY-5-CHLORO ACETOPHENONE 1-(5-CHLORO-2-HYDROXYPHENYL)-1-ETHANONE 1-(5-CHLORO-2-HYDROXYPHENYL)ETHANONE AKOS BB-6937 5'-CHLORO-2'-HYDROXYACETOPHENONE 5'-Chloro-2'-hydroxyacetophenone 99% 5'-Chloro-2'-hydroxyacetophenone, 98%+ SALOR-INT L497495-1EA 2-Acetyl-4-chlorophenol oro-2'-hydroxyacetophenone 2'-hydroxy-5'-chlorophenone 1-(5 CHOLRO-2-HYDROXYPHENYL)ETHANONE JRH-01003, 1-(5-Chloro-2-hydroxyphenyl)ethanone, 97% 1-(3-chlorophenyl)-2-hydroxyethan-1-one 1-(5-CHLORO-2-HYDROXYPHENYL)ETHAN-1-ONE 5-CHLORO-2-HYDROXYACETOPHENONE 2-HYDROXY-5-CHLOROACETOPHENONE -99+% CA 2 HYDROXY-5-CHLOROACETOPHENONE-99+% 5'-Chloro-2'-hydroxyacetophenone 2'-Hydroxy-5'-chloroacetophenone 1450-74-4 ClC6H3OHCOCH3 Organic Building Blocks Ketones Building Blocks C7 to C8 Carbonyl Compounds Aromatic Acetophenones & Derivatives (substituted) Phenoles and thiophenoles Adehydes, Acetals & Ketones Chlorine Compounds Phenols C7 to C8 Carbonyl Compounds Ketones ADVANCED INT.