Chinese english Japanese Germany Korea

R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST

R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST Structure
CAS No.
125-58-6
Chemical Name:
R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST
Synonyms
levothyl;l-polamivet;(R)-Methadone;(-)-Diaminone;Laevomethadon;levomethadone;(6r)-methadone;4-diphenyl-6-(dimethylamino)-l-3-heptanon;4-diphenyl-6-(dimethylamino)-(r)-3-hetpanon;l-6-(dimethylamino)-4,4-diphenyl-3-heptanone
CBNumber:
CB3498242
Molecular Formula:
C21H27NO
Molecular Weight:
309.44518
MOL File:
125-58-6.mol
Modify Date:
2023/5/4 17:34:32
Request For Quotation

R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST Properties

Melting point 99°C
Boiling point 449.71°C (rough estimate)
Density 1.0350 (rough estimate)
refractive index 1.5614 (estimate)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300-H412-H336
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P273-P501-P261-P271-P304+P340-P312-P403+P233-P405-P501

R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST Chemical Properties,Uses,Production

Purification Methods

This pharmacologically active (against narcotic addiction) enantiomer was obtained by optical resolution (using D-tartaric acid) of the racemate and was purified by precipitation of the hydrochloride from aqueous solution at pH >6, dried and recrystallised from propan-2-ol. The R-hydrochloride [5967-73-7], when recrystallised from propan-2-ol, has m 245-246o, [] D 20 -169o (c 2, EtOH). The S-(+)-enantiomer [5653-8-5] also recrystallises from propan-2-ol and has recorded m of 100-101o, [] D 25 + 26o (c 1.2, H2O). The S-hydrochloride [15284-15-8], when crystallised from propan-2-ol, has m 243-244o, [] D 20 +169o (c 2, EtOH). [Larsen et al. J Am Chem Soc 70 4194 1948, Brode & Hill J Org Chem 13 191 1948, Schultz et al. J Am Chem Soc 69 2454 1947, Easton et al. J Am Chem Soc 69 2941 1947, Winter & Flataker J Pharmacol Exp Ther 98 305 1950, Beilstein 14 III 278, 1 4 III/IV 300.]

R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST Preparation Products And Raw materials

Raw materials

Preparation Products

125-58-6(R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST)Related Search:

Methadone hydrochloride (+/-)-METHADONE 1,1-Diphenylacetone normethadone R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST
METHADONE
chevron_left

1of2

chevron_right
l-6-(dimethylamino)-4,4-diphenyl-3-heptanone levomethadone levothyl l-polamivet Laevomethadon (-)-Diaminone (R)-Methadone 3-Heptanone,6-(diMethylaMino)-4,4-diphenyl-, (6R)- R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST (6r)-methadone (r)-6-(dimethylamino)-4,4-diphenyl-3-heptanone 4-diphenyl-6-(dimethylamino)-(r)-3-hetpanon 4-diphenyl-6-(dimethylamino)-l-3-heptanon (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one 125-58-6