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2,4-Piperadinedione

2,4-Piperadinedione Structure
CAS No.
50607-30-2
Chemical Name:
2,4-Piperadinedione
Synonyms
Piperidine-2,4-dione;PIPERIDIN-2,4-DIONE;2,4-Piperidinedione;2,4-PIPERADINEDIONE;2,4-Dioxopiperidine;2,4-PiperadinedioneE;2,4-Diketopiperidine;2,4-Piperidinedione>Piperidine-2,4-dione 97%;2,4-Piperidinedione, 95+%
CBNumber:
CB3511804
Molecular Formula:
C5H7NO2
Molecular Weight:
113.11
MOL File:
50607-30-2.mol
MSDS File:
SDS
Modify Date:
2023/9/12 16:22:06
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2,4-Piperadinedione Properties

Melting point 98.0 to 102.0 °C
Boiling point 362.1±35.0 °C(Predicted)
Density 1.184±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka 12.00±0.70(Predicted)
color White to Orange to Green
InChIKey RDNZDMDLRIQQAX-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H317-H319-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38-43
Safety Statements  26-36/37
RIDADR  UN 3335
WGK Germany  3
HS Code  2933790090

2,4-Piperadinedione price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 759368 2,4-Piperidinedione 97% 50607-30-2 250MG ₹6754.8 2022-06-14 Buy
TCI Chemicals (India) P2296 2,4-Piperidinedione min. 98.0 % 50607-30-2 200MG ₹3800 2022-05-26 Buy
TCI Chemicals (India) P2296 2,4-Piperidinedione min. 98.0 % 50607-30-2 1G ₹10100 2022-05-26 Buy
Product number Packaging Price Buy
759368 250MG ₹6754.8 Buy
P2296 200MG ₹3800 Buy
P2296 1G ₹10100 Buy

2,4-Piperadinedione Chemical Properties,Uses,Production

Description

2,4-Piperidinedione is an important piperidine ring-containing intermediate, and its 2,4-piperidinedione, as a characteristic fragment, is widely used as an intermediate in the synthesis of ibrutinib and paliperidone drugs.

Chemical Properties

White to light yellow solid

Preparation

The synthesis of 2,4-Piperidinedione involved dissolving 400 mg (2.34 mmol, 1.00 eq.) of Methyl 2,4-dioxo-piperidine-3-carboxylate in a mixture of acetonitrile (20 mL) and water (0.2 mL). The solution was then heated to approximately 86° C. and maintained at this temperature for around 4 hours. After completion of the reaction, the solvent was removed under vacuum, leaving behind a residue of 2,4-Piperidinedione. This residue was further purified using silica gel column chromatography with a mobile phase consisting of dichloromethane and methanol in a ratio of 100:1. The target product, 2,4-Piperidinedione, was obtained as a white solid, with a yield of 27%, corresponding to 70 mg.

2,4-Piperadinedione Preparation Products And Raw materials

Raw materials

PICRIC ACID Benzyltrimethylammonium hydroxide Sodium Ethanethiol N-phenylsulfanylbenzenesulfenamide
Ethyl acrylate Ethyl malonyl chloride
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Preparation Products

4-hydroxy-2-Piperidinone 2,4-Piperidinedione,3-[(dimethylamino)methylene]-(9CI)

2,4-Piperadinedione Suppliers

Global( 239)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BTC pharm India +918790379245 AndhraPradesh, India 1269 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
ANAXLABORATORIES PRIVATE LIMITED +91-9177075735 Telangana, India 686 58 Inquiry
TSK Lifesciences 91-9397306789 Hyderabad, India 246 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20294 58 Inquiry
Supplier Advantage
BTC pharm India 58
JSK Chemicals 58
ANAXLABORATORIES PRIVATE LIMITED 58
TSK Lifesciences 58
CHEMSWORTH 30
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
Alfa Aesar 58
Henan Fengda Chemical Co., Ltd 58

2,4-Piperadinedione Spectrum

2,4-Piperadinedione(50607-30-2)1HNMR

50607-30-2(2,4-Piperadinedione)Related Search:

DROPERIDOL Haloperidol 2',4'-Dichloroacetophenone 2,2,6,6-Tetramethyl-4-piperidinol Triacetonediamine
METHYPRYLON Diphenoxylate 3,3-DIMETHYLGLUTARIMIDE DL-Glutethimide 2,6-Dioxopiperidine-3-ammonium chloride
Aminoglutethimide Ethyl 4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate 1-benzylpiperidine-3,5-dione 5-ETHYL-2,4-PIPERIDINEDIONE Antineoplaston A10
N-Benzyl-2,6-piperidinedion 6-Phenylazaperhydroine-2,4-dione 3-ETHYL-3-METHYLGLUTARIMIDE
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piperidine-2,4-dione, dihydropyridine-4,6-dione, 2,4-dioxopiperidine, 2,4-piperidinedione, piperidin-2,4-dione, 2,4-diketopiperidine, Piperidine-2,4-dione 2,4-PIPERADINEDIONE 2,4-Piperidinedione dihydropyridine-4,6-dione 2,4-Dioxopiperidine 2,4-Piperidinedione, 95+% 2,4-Diketopiperidine 2,4-PiperadinedioneE Piperidine-2,4-dione 97% 2,4-Piperidinedione> 2,4-Piperidinedione,Piperidine-2,4-dione Piperidine-2,4-dione PIPERIDIN-2,4-DIONE 2,4-Piperidinedione (9CI, ACI) 50607-30-2 Pharmaceutical intermediate Heterocycles series