2,4-Piperadinedione
![2,4-Piperadinedione Structure](CAS/GIF/50607-30-2.gif)
- CAS No.
- 50607-30-2
- Chemical Name:
- 2,4-Piperadinedione
- Synonyms
- Piperidine-2,4-dione;PIPERIDIN-2,4-DIONE;2,4-Piperidinedione;2,4-PIPERADINEDIONE;2,4-Dioxopiperidine;2,4-PiperadinedioneE;2,4-Diketopiperidine;2,4-Piperidinedione>Piperidine-2,4-dione 97%;2,4-Piperidinedione, 95+%
- CBNumber:
- CB3511804
- Molecular Formula:
- C5H7NO2
- Molecular Weight:
- 113.11
- MOL File:
- 50607-30-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/12 16:22:06
Melting point | 98.0 to 102.0 °C |
---|---|
Boiling point | 362.1±35.0 °C(Predicted) |
Density | 1.184±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
form | powder to crystal |
pka | 12.00±0.70(Predicted) |
color | White to Orange to Green |
InChIKey | RDNZDMDLRIQQAX-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H317-H319-H335 |
Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38-43 |
Safety Statements | 26-36/37 |
RIDADR | UN 3335 |
WGK Germany | 3 |
HS Code | 2933790090 |
2,4-Piperadinedione price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 759368 | 2,4-Piperidinedione 97% | 50607-30-2 | 250MG | ₹6754.8 | 2022-06-14 | Buy |
TCI Chemicals (India) | P2296 | 2,4-Piperidinedione min. 98.0 % | 50607-30-2 | 200MG | ₹3800 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2296 | 2,4-Piperidinedione min. 98.0 % | 50607-30-2 | 1G | ₹10100 | 2022-05-26 | Buy |
2,4-Piperadinedione Chemical Properties,Uses,Production
Description
2,4-Piperidinedione is an important piperidine ring-containing intermediate, and its 2,4-piperidinedione, as a characteristic fragment, is widely used as an intermediate in the synthesis of ibrutinib and paliperidone drugs.
Chemical Properties
White to light yellow solid
Preparation
The synthesis of 2,4-Piperidinedione involved dissolving 400 mg (2.34 mmol, 1.00 eq.) of Methyl 2,4-dioxo-piperidine-3-carboxylate in a mixture of acetonitrile (20 mL) and water (0.2 mL). The solution was then heated to approximately 86° C. and maintained at this temperature for around 4 hours. After completion of the reaction, the solvent was removed under vacuum, leaving behind a residue of 2,4-Piperidinedione. This residue was further purified using silica gel column chromatography with a mobile phase consisting of dichloromethane and methanol in a ratio of 100:1. The target product, 2,4-Piperidinedione, was obtained as a white solid, with a yield of 27%, corresponding to 70 mg.
2,4-Piperadinedione Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
ANAXLABORATORIES PRIVATE LIMITED | +91-9177075735 | Telangana, India | 686 | 58 | Inquiry |
TSK Lifesciences | 91-9397306789 | Hyderabad, India | 246 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20294 | 58 | Inquiry |
Supplier | Advantage |
---|---|
BTC pharm India | 58 |
JSK Chemicals | 58 |
ANAXLABORATORIES PRIVATE LIMITED | 58 |
TSK Lifesciences | 58 |
CHEMSWORTH | 30 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
Henan Fengda Chemical Co., Ltd | 58 |
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