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METHOTREXATE DIMETHYL ESTER

METHOTREXATE DIMETHYL ESTER Structure
CAS No.
34378-65-9
Chemical Name:
METHOTREXATE DIMETHYL ESTER
Synonyms
DiMethyl Methotrexate;Methotrexate Impurity J;Methotrexate EP Impurity J;METHOTREXATE DIMETHYL ESTER;Methotrexate Impurity 10(EP-J);Methotrexate Impurity 10(Methotrexate EP Impurity J);Methotrexate EP Impurity J(Amethopterin EP Impurity J);Methotrexate EP Impurity J (Methotrexate Dimethyl Ester);dimethyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate;(S)-dimethyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
CBNumber:
CB3649277
Molecular Formula:
C22H26N8O5
Molecular Weight:
482.49244
MOL File:
34378-65-9.mol
Modify Date:
2023/4/23 13:52:06

METHOTREXATE DIMETHYL ESTER Properties

Melting point 134-140°C
Density 1.392±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 13.46±0.46(Predicted)
form Solid
color Light Yellow to Dark Red
CAS DataBase Reference 34378-65-9

METHOTREXATE DIMETHYL ESTER Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

METHOTREXATE DIMETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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METHOTREXATE DIMETHYL ESTER DiMethyl Methotrexate N-[4-[[(2,4-DiaMino-6-pteridinyl)Methyl]MethylaMino]benzoyl]-L-glutaMic Acid DiMethyl Ester Methotrexate EP Impurity J(Amethopterin EP Impurity J) Methotrexate Impurity J Methotrexate EP Impurity J Methotrexate Impurity 10(EP-J) (S)-dimethyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate Methotrexate Impurity 10(Methotrexate EP Impurity J) Methotrexate EP Impurity J (Methotrexate Dimethyl Ester) dimethyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1,5-dimethyl ester 34378-65-9 C22H26N8O5 Intermediates & Fine Chemicals Pharmaceuticals