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BISNORCHOLENALDEHYDE

BISNORCHOLENALDEHYDE Structure
CAS No.
3986-89-8
Chemical Name:
BISNORCHOLENALDEHYDE
Synonyms
BNKY018-PG01;Bisnorcholeldehyde;KETOBISNORALDEHYDE;Bisnorcholenaldehyde;Progesterone Impurity 7;Progesterone Impurity 24;Progesterone EP Impurity I;Didroprogesterone impurity 2;Progesterone EP Impurity I-02;(20S)-20-Formylpregn-4-en-3-one
CBNumber:
CB3670455
Molecular Formula:
C22H32O2
Molecular Weight:
328.49
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2024/3/19 9:41:09

BISNORCHOLENALDEHYDE Properties

Melting point 159-160 °C
Boiling point 459.4±14.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H351-H362-H360
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313

BISNORCHOLENALDEHYDE Chemical Properties,Uses,Production

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 30)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
BIONNA MEDICINE CO.,LTD 01056380788-8515; +8618518759099 China 52 58 Inquiry
Shenzhen Excellent Biomedical Technology Co.,Ltd. +86-0755-26050679 +86-15915472436 China 1031 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 China 9971 58 Inquiry
Shenzhen Excellent Biomedical Technology Co., Ltd. 18318671572 China 4993 58 Inquiry
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657 China 10614 58 Inquiry
TOSUN PHARM 020-61855200 13326451905 China 7565 58 Inquiry
KETOBISNORALDEHYDE 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE Progesterone EP Impurity I Progesterone Impurity 7 Progesterone EP Impurity I (S-isomer) (20S)-3-oxopregn-4-ene-20-carboxaldehyde BNKY018-PG01 Bisnorcholeldehyde Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal 3-Oxo-pregn-4-ene-20α- carboxaldehyde Progesterone Impurity 24 (20S)-20-Formylpregn-4-en-3-one (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity) Didroprogesterone impurity 2 Progesterone EP Impurity I-02 Bisnorcholenaldehyde 3986-89-8