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ChemicalBook > Product Catalog >Organic Chemistry >Hydrocarbons and derivatives >Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Structure
CAS No.
503070-57-3
Chemical Name:
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
Synonyms
BNKY020-VT06;CAS 503070-57-3;ethoxymethyl]​Bromohexyloxy)​Vilanterol Impurity 80;Vilanterol Impurity 28;Vilanterol intermediate;BROMOHEXYL-OXY- ETHOXYMETHYLCHLOROBENZENE;2-((2-((6-bromohexyl)oxy)methyl)-1,3-dichlorobenzene;2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
CBNumber:
CB62563268
Molecular Formula:
C15H21BrCl2O2
Molecular Weight:
384.14
MOL File:
503070-57-3.mol
Modify Date:
2024/3/18 11:37:55
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Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Properties

Boiling point 420.8±45.0 °C(Predicted)
Density 1.335±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Chemical Properties,Uses,Production

Uses

2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene is an intermediate in the synthesis of Vilanterol Trifenatate-d4 (V260002). Vilanterol Trifenatate (V260000) is a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.

Synthesis

100mL single-necked flask, under a nitrogen atmosphere, 2-((2,6-dichlorobenzyl)oxy)ethan-1-ol (3 g, 13.5 mmol) was dissolved in 1,6-dibromo hexane (9.7 g, 40.5 mmol) tetrabutylammonium bromide (432 mg, 1.35mmol) and 50% sodium hydroxide solution (2.5g, 62.1 mmol) was added and reacted at room temperature for 16 hours. Dichloromethane (50 mL), washed successively with water (50 mL) and saturated brine (50 mL), dried over the organic phase, filtered, concentrated and purified on a silica gel column (ethyl acetate/petroleum ether = 1/12) to give a pale yellow oil Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro.
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Preparation Products And Raw materials

Raw materials

Preparation Products

Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Suppliers

Global( 161)Suppliers
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ANWITA APIS +919000311012 Hyderabad, India 198 58 Inquiry
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ANWITA APIS 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Abv Laboratories Private Limited 58
Anhui Dexinjia Biopharm Co., Ltd 58
BIONNA MEDICINE CO.,LTD 58
Baoji Guokang Healthchem co.,ltd 58
Capot Chemical Co.,Ltd. 60
Shanghai Daken Advanced Materials Co.,Ltd 58

503070-57-3(Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro)Related Search:

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21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol BISNORCHOLENALDEHYDE tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
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Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 2-[2-(6-BroMohexyloxy)ethoxyMethyl]-1,3-dichlorobenzene Vilanterol intermediate 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Vilanterol Impurity 28 BNKY020-VT06 CAS 503070-57-3 BROMOHEXYL-OXY- ETHOXYMETHYLCHLOROBENZENE 2- [2- (6-bromohexaoxy) ethoxymethyl] -1,3-dichlorobenzene Vilanterol Impurity 80 2-((2-((6-bromohexyl)oxy)methyl)-1,3-dichlorobenzene Bromohexyloxy)​ ethoxymethyl]​ 503070-57-3 503070-53-0 C15H21BrCl2O2 Intermediate 503070-57-3