ROBISON ESTER MONOSODIUM SALT
- CAS No.
- 54010-71-8
- Chemical Name:
- ROBISON ESTER MONOSODIUM SALT
- Synonyms
- G6P sodium salt;Einecs 258-921-0;D-Glucose 6-phosphat;Sodium (2R,3R,4S,5R);G-6-P Na, Robison ester;Sodium Glucose-6-Phosphate;a-D-Glucose-6-Phosphate, Na;D-Glucose 6-phosphate sodium;ROBISON ESTER MONOSODIUM SALT;D-Glucose6-phosphatesodiumsal
- CBNumber:
- CB3681824
- Molecular Formula:
- C6H14NaO9P
- Molecular Weight:
- 284.13
- MOL File:
- 54010-71-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 17:35:16
| Melting point | 204 °C (dec.)(lit.) |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: 50 mg/mL, clear, colorless to very faintly yellow |
| form | crystalline |
| BRN | 5787568 |
| InChI | InChI=1/C6H13O9P.Na.H/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;;/h1,3-6,8-11H,2H2,(H2,12,13,14);;/t3-,4+,5+,6+;;/s3 |
| InChIKey | RUFPTDNHMAGVMV-IWNCBHIWNA-N |
| SMILES | [C@@H](O)([C@H](O)COP(O)(O)=O)[C@H](O)[C@@H](O)C=O.[NaH] |&1:0,2,10,12,r| |
| CAS DataBase Reference | 54010-71-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 29400000 |
ROBISON ESTER MONOSODIUM SALT price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G7879 | D-Glucose 6-phosphate sodium salt crystalline | 54010-71-8 | 500MG | ₹4427.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G7879 | D-Glucose 6-phosphate sodium salt crystalline | 54010-71-8 | 1G | ₹9774.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G7879 | D-Glucose 6-phosphate sodium salt crystalline | 54010-71-8 | 5G | ₹33828.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G7879 | D-Glucose 6-phosphate sodium salt crystalline | 54010-71-8 | 25G | ₹122950.35 | 2022-06-14 | Buy |
ROBISON ESTER MONOSODIUM SALT Chemical Properties,Uses,Production
Description
D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis. It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver. D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways. Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.
Chemical Properties
White crystalline solid
General Description
A glycolytic intermediate that also acts as a competitive and reversible inhibitor of hexokinase. Useful in creating an ATP-regenerating system. Causes the release of mitochondrially bound hexokinase in muscle.
Purification Methods
It can be freed from metal impurities as described for glucose-1-phosphate. The solubility of the Na salt is 5% in H2O at 20o. Its barium salt can be purified by solution in dilute HCl and precipitation by neutralising the solution. The precipitate is washed with small volumes of cold water and dried in air. Alternatively the barium salt is dissolved in H2O, 4volumes of EtOH are added, the precipitate is collected, washed with 90% EtOH, absolute EtOH, 75% EtOH/25% Et2O, 25% EtOH/75% Et2O and finally dry Et2O. The dry Barium salt has [] D +17.9o (c 1, H2O). [Beilstein 1 IV.]
ROBISON ESTER MONOSODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5999 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
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