Rebaudioside A
- CAS No.
- 58543-16-1
- Chemical Name:
- Rebaudioside A
- Synonyms
- REBAUDIOSIDE;Steviol Glycoside;Reb A;4G-S;Rebiana;Reb-A 97;Pure Via;Glycoside X;Lebaldide A;Glycoside A3
- CBNumber:
- CB3736050
- Molecular Formula:
- C44H70O23
- Molecular Weight:
- 967.01
- MOL File:
- 58543-16-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:06
| Melting point | 235°C(lit.) |
|---|---|
| Boiling point | 1102.8±65.0 °C(Predicted) |
| Density | 1.59±0.1 g/cm3(Predicted) |
| vapor pressure | 0-1198Pa at 20-50℃ |
| FEMA | 4601 | REBAUDIOSIDE A |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Sparingly) |
| form | Solid |
| pka | 12.51±0.70(Predicted) |
| color | White to Off-White |
| optical activity | [α]/D -33.0±3.0°, c = 1% in H2O |
| BRN | 6470556 |
| Stability | Hygroscopic |
| LogP | -1-2.61 at 20-25℃ and pH7 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | NZ8174800 |
| HS Code | 29389090 |
Rebaudioside A price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 38462 | Rebaudioside A analytical standard | 58543-16-1 | 10MG | ₹20340.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 01432 | Rebaudioside A ≥96% (HPLC) | 58543-16-1 | 10G | ₹10186.33 | 2022-06-14 | Buy |
| TCI Chemicals (India) | R0095 | Rebaudioside A | 58543-16-1 | 5G | ₹5200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | R0095 | Rebaudioside A | 58543-16-1 | 25G | ₹11100 | 2022-05-26 | Buy |
| ottokemi | R 7347 | Rebaudioside A 98% | 58543-16-1 | 5gm | ₹4689 | 2022-05-26 | Buy |
Rebaudioside A Chemical Properties,Uses,Production
Description
Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol , a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.
Chemical Properties
White powder
Uses
Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect on blood glucose. As a result, Rebaudiosi de A is known for its application in treatment of many diseases like diabetes, high blood pressure and weight loss in some places. It is used as a food additive and in dietary supplements.
Definition
Rebaudioside A is a rebaudioside that is rubusoside in which the hydroxy groups at positions 3 and 4 of the beta-D-glucopyranosyloxy group at the 13alpha position have both been converted to the corresponding beta-D-glucopyranoside. It has a role as a sweetening agent. It is a beta-D-glucoside, a tetracyclic diterpenoid and a rebaudioside. It derives from a rubusoside and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.
benefits
Zero calories
No carbohydrate
Does not raise blood glucose or insulin levels (Zero Index Glycemic), safe for people with diabetes
Keto, Vegan, and Gluten-Free
Biological Activity
Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol, a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.
Safety
High-purity (95% minimum) of individual or combined steviol glycosides can be considered as GRAS (Generally Recognized as Safe) by the FDA. For example, FDA had no questions regarding Guilin Layn's conclusion that its reb A (≥97% by weight (w/w)) is GRAS as a table top sweetener and as a general purpose sweetener in foods, excluding meat and poultry products and infant formulas.
Its safety has also been approved by the EFSA, JECFA, FSANZ and other authorities.
Rebaudioside A Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| AnalyticsStanza Inc | +91-7032031309 +91-7032031309 | Hyderabad, India | 227 | 58 | Inquiry |
| Natural Remedies Pvt Ltd | +91 (80) 4020-9999 | New Delhi, India | 110 | 50 | Inquiry |
| Zero Enthalpy Labs Private Limited | 08048250474Ext 201 | Haryana, India | 1 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |