NOBILETIN
- CAS No.
- 478-01-3
- Chemical Name:
- NOBILETIN
- Synonyms
- hexamethoxyflavone;Chuanpi glycosides;biletin;Nobiletin, 98%, from Citrus nobilis Lour.;NOBILETIN;Nobiletin>Chuanchenpi Su;Nobiletin (6CI);Nobiletin, >=98%;Nobiletin 478-01-3
- CBNumber:
- CB3740677
- Molecular Formula:
- C21H22O8
- Molecular Weight:
- 402.39
- MOL File:
- 478-01-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:06
| Melting point | 136.0 to 140.0 °C |
|---|---|
| Boiling point | 587.9±50.0 °C(Predicted) |
| Density | 1.244±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 10 mg/ml) |
| form | Solid |
| color | White |
| BRN | 360887 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | MRIAQLRQZPPODS-UHFFFAOYSA-N |
| CAS DataBase Reference | 478-01-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | DJ3052200 |
| HS Code | 29329990 |
NOBILETIN price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N1538 | Nobiletin ≥97% | 478-01-3 | 5MG | ₹19463.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N1538 | Nobiletin ≥97% | 478-01-3 | 10MG | ₹47597.53 | 2022-06-14 | Buy |
| TCI Chemicals (India) | N0871 | Nobiletin | 478-01-3 | 10MG | ₹8800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0871 | Nobiletin | 478-01-3 | 100MG | ₹15000 | 2022-05-26 | Buy |
NOBILETIN Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein.
Definition
ChEBI: A methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively.
benefits
Nobiletin improved cognitive deficits and the pathological features of AD, such as Aβ pathology, hyperphosphorylation of tau, and oxidative stress, in animal models of AD. In addition, nobiletin improved motor and cognitive deficits in PD animal models. These observations suggest that nobiletin has the potential to become a novel drug for the treatment and prevention of neurodegenerative diseases such as AD and PD.
NOBILETIN Preparation Products And Raw materials
Raw materials
Phenol, 2,3,4-trimethoxy-, 1-formate
1,2,3,4-TETRAMETHOXYBENZENE
1,3-Propanedione, 1-(3,4-dimethoxyphenyl)-3-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,8-dihydroxy-6,7-dimethoxy-
1-(3,4-dimethoxybenzoyl)-1H-1,2,3-benzotriazole
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Global( 335)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| PNP Biotech Co. Ltd | +8618516098983 | China | 1001 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5959 | 58 | Inquiry |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | China | 990 | 58 | Inquiry |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | China | 301 | 58 | Inquiry |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9337 | 55 | Inquiry |
Related articles
- Nobiletin: A Promising Citrus-Derived Compound with Anti-Cancer and Anti-Immune-Modulating Properties
- Nobiletin, from citrus fruits, exhibits anti-cancer, anti-inflammatory, and antioxidant properties, making it a promising cand....
- Feb 5，2024
- Nobiletin benefits
- Nobiletin has been proved biological activitys such as having antitumor, antiviral, blood sugar lowering, neuroprotective, its....
- Dec 15，2022
478-01-3(NOBILETIN)Related Search:
Nobiletin, froM Citrus nobilis Lour.
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-
Nobiletin, >=98%
NOBILETIN
3',4',5,6,7,8-HEXAMETHOXYFLAVONE
NOBILETIN WITH HPLC
NOBILETIN, 20% (TECHNICAL GRADE)
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-
5,6,7,8-tetramethoxy-
Nobiletin，Hexamethoxyflavone
2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromen-4-one
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromone
Flavone, 5,6,7,8,3',4'-hexamethoxy
Nobiletin 478-01-3
Nobiletin>
Nobiletin (100 mg) (2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one)
hexamethoxyflavone
biletin
Chuanpi glycosides
Nobiletin, 98%, from Citrus nobilis Lour.
Polymethoxylated Flavones (PMFs)
2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one
Nobiletin (6CI)
Chuanchenpi Su
478-01-3
C21H22O8
chemical reagent
pharmaceutical intermediate
Inhibitors
natural product
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Hexa-substituted Flavones
CITRIMORE
478-01-3