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URSODEOXYCHOLIC-2,2,4,4-D4 ACID

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Structure
CAS No.
347841-46-7
Chemical Name:
URSODEOXYCHOLIC-2,2,4,4-D4 ACID
Synonyms
Ursodeoxycholic-d4 Acid;2H4]-Ursodeoxycholic Acid;URSODEOXYCHOLIC-2,2,4,4-D4 ACID;Urosodeoxycholic Acid Impurity 28;Ursodeoxycholic acid-[d4] (Solution);Ursodiol-d4 (Ursodeoxycholic Acid-d4);Ursodeoxycholic Acid-2,2,4,4-d4 (Major);Ursodeoxycholic Acid-d4 MaxSpec? Standard;*Dronedarone Impurity 37 ( Tributylamine);URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY
CBNumber:
CB3755802
Molecular Formula:
C24H40O4
Molecular Weight:
392.58
MOL File:
347841-46-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:14
Request For Quotation

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Properties

storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly),
form Solid
color White to Off-White
Stability Hygroscopic

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production

Description

Ursodeoxycholic acid-d4 (UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

Uses

Ursodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials

Raw materials

Preparation Products

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Suppliers

Global( 40)Suppliers
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CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
ChemStrong Scientific Co.,Ltd 56
TCI (Shanghai) Chemical Trading Co., Ltd. 58
Manhag Testing Technology Co., Ltd 58
HX Pharmaceutical technology co., LTD 58
Shanghai isotope chemical co.,ltd 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Nanjing Shizhou Biology Technology Co.,Ltd 58

347841-46-7(URSODEOXYCHOLIC-2,2,4,4-D4 ACID)Related Search:

URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE Glycoursodeoxycholic Acid URSODEOXYCHOLIC ACID-24-13C Ursodeoxycholic acid Ursodeoxycholic Acid-d5
Ursodeoxycholic Acid Methyl Ester-d5 Taurolithocholic-d4 Acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid α-Muricholic Acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid
(4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Ursodeocycholic Acid-[d4]-3-Sulfate Sodium Salt Ursodeocycholic Acid-3-Sulfate Sodium Salt (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid
3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID LITHOCHOLIC ACID 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
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URSODEOXYCHOLIC-2,2,4,4-D4 ACID Ursodeoxycholic-d4 Acid (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Ursodiol-d4 (Ursodeoxycholic Acid-d4) Ursodeoxycholic acid-[d4] (Solution) URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL Ursodeoxycholic Acid-d4 MaxSpec? Standard Ursodeoxycholic Acid-2,2,4,4-d4 (Major) (4R)-4-[(3R,5S,7S,8R,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 2H4]-Ursodeoxycholic Acid Urosodeoxycholic Acid Impurity 28 *Dronedarone Impurity 37 ( Tributylamine) 347841-46-7 C24H36D4O4 Bile Acids - 13C & 2H