ChemicalBook > Product Catalog >Organic Chemistry >Carboxylic acids and derivatives >Carboxylic Acid Anhydrides >HEXANOIC ANHYDRIDE

HEXANOIC ANHYDRIDE

HEXANOIC ANHYDRIDE Structure
CAS No.
2051-49-2
Chemical Name:
HEXANOIC ANHYDRIDE
Synonyms
N-HEXANOIC ANHYDRIDE;CAPROIC ANHYDRIDE;hexanoylhexanoate;N-HEXOIC ANHYDRIDE;Capronic anhydride;Hexanoyl anhydride;n-Capriocanhydride;HEXANOIC ANHYDRIDE;N-CAPROIC ANHYDRIDE;N-CAPRONIC ANHYDRIDE
CBNumber:
CB3766110
Molecular Formula:
C12H22O3
Molecular Weight:
214.3
MOL File:
2051-49-2.mol
MSDS File:
SDS
Modify Date:
2023/11/13 19:05:53

HEXANOIC ANHYDRIDE Properties

Melting point -40 °C
Boiling point 246-248 °C (lit.)
Density 0.928 g/mL at 20 °C (lit.)
vapor pressure 2.9Pa at 25℃
refractive index n20/D 1.428(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility ethanol: soluble1g/10 mL, clear, colorless
form Liquid
color Clear colorless to light yellow
explosive limit 0.7%(V)
Water Solubility Hydrolyzes in water.
Sensitive Moisture Sensitive
BRN 1776561
LogP 4.45 at 25℃
CAS DataBase Reference 2051-49-2(CAS DataBase Reference)
EPA Substance Registry System Hexanoic acid, anhydride (2051-49-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29159000
NFPA 704
1
3 0

HEXANOIC ANHYDRIDE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 21580 Hexanoic anhydride purum, ≥97.0% (GC) 2051-49-2 50ML ₹1872.73 2022-06-14 Buy
Sigma-Aldrich(India) 21580 Hexanoic anhydride purum, ≥97.0% (GC) 2051-49-2 250ML ₹7112.03 2022-06-14 Buy
Sigma-Aldrich(India) 194530 Hexanoic anhydride 97% 2051-49-2 50G ₹2760.38 2022-06-14 Buy
Sigma-Aldrich(India) 194530 Hexanoic anhydride 97% 2051-49-2 250G ₹5055.28 2022-06-14 Buy
ALFA India ALF-B23756-30 Hexanoic anhydride, 98% 2051-49-2 250g ₹4159 2022-05-26 Buy
Product number Packaging Price Buy
21580 50ML ₹1872.73 Buy
21580 250ML ₹7112.03 Buy
194530 50G ₹2760.38 Buy
194530 250G ₹5055.28 Buy
ALF-B23756-30 250g ₹4159 Buy

HEXANOIC ANHYDRIDE Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Hexanoic anhydride has been used in:

  • green synthesis of esters of acyclovir (acyclovir prodrugs)
  • preparation of hexanoyl-modified chitosan nanoparticles and chitosan-based polymeric surfactants via N-acylation of chitosans

Preparation

To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg).
Preparation of n-Caproic Anhydride

HEXANOIC ANHYDRIDE Preparation Products And Raw materials

Global( 203)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4542 58 Inquiry
JPN Pharma Pvt Ltd +919833233531 Maharashtra, India 33 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Proto Chemicals Industries +91-9867299770 +91-9029078381 Maharashtra, India 23 58 Inquiry
Ishant Polychem +91-2223445496 +91-9819878422 Maharashtra, India 24 58 Inquiry
Proto Chemicals Industries 08048601271 Mumbai, India 15 58 Inquiry
Ralington Pharma. 91-79-48911722 Gujarat, India 311 58 Inquiry
Ishant Polychem 08048372582Ext 338 Mumbai, India 21 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
N-BUTYLACETIC ANHYDRIDE N-CAPRONIC ANHYDRIDE N-CAPROIC ANHYDRIDE N-HEXOIC ANHYDRIDE PENTYLFORMIC ANHYDRIDE N-CAPROICANHYDRIDE=HEXANOICANHYDRIDE Bis(hexanoic)anhydride Biscaproic anhydride Bishexanoic anhydride Dihexanoic anhydride Hexanoic anhydride,97% Hexanoic anhydride, 97% 250GR Hexanoic anhydride, 97% 50GR Hexanoic acid,1,1'-anhydride Hexanoic anhydride 97% Caproic acid anhydride Capronic acid anhydride Capronic anhydride hexanoicacid,anhydride Hexanoicacidanhydride Hexanoyl anhydride n-Capriocanhydride n-Hexanoic acid anhydride HEXANOIC ANHYDRIDE CAPROIC ANHYDRIDE 6-benzamido-2-bromohexanoic acid Hexanoic Anhydride > hexanoylhexanoate HEXANOIC ANHYDRIDE ISO 9001:2015 REACH High Quality HEXANOIC ANHYDRIDE CAS 2051-49-2 with Free sample N-HEXANOIC ANHYDRIDE 2051-49-2 C12H22O3 CH3CH24CO2O C5H11CO2O Carboxylic Acid Anhydrides Carbonyl Compounds Building Blocks Organic Building Blocks Pharmaceutical Intermediates