1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE

CAS No.: 180046-99-5

Chemical Name:: 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE

Synonyms: SDZ NKT 343;1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE;L-Alaninamide, 1-[[(2-nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-

CBNumber:: CB3839272

Molecular Formula:: C33H33N5O5

Molecular Weight:: 579.65

MOL File:: 180046-99-5.mol

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Properties

Boiling point	892.8±65.0 °C(Predicted)
Density	1.327±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble to 100 mM in DMSO and to 100 mM in ethanol
form	Powder
pka	11.66±0.70(Predicted)

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Chemical Properties,Uses,Production

Uses

SDZ NKT 343 is a potent human NK1 tachykinin receptor antagonist.

Biological Activity

Highly selective human tachykinin NK 1 receptor antagonist (IC 50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK 2 and NK 3 receptors. Potently antagonizes SP-induced Ca 2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo .

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Suppliers

Global( 25)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
BOC Sciences		USA	0	65	Inquiry
Service Chemical Inc.	888-895-6920	Germany	6373	71	Inquiry
3B Scientific Corporation	847.281.9822	United States	6744	47	Inquiry
CARBONE SCIENTIFIC CO.,LTD	+44(0)870 486 8629	United Kingdom	6682	30	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
ApexBio Technology	+ 1-832-696-8203	United States	6254	58	Inquiry
Shanghai Haoyang Biological Technology Co., Ltd.	021-54046790 15121098156	CHINA	2905	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
BOC Sciences	65
Service Chemical Inc.	71
3B Scientific Corporation	47
CARBONE SCIENTIFIC CO.,LTD	30
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Tocris Bioscience	77
ApexBio Technology	58
Shanghai Haoyang Biological Technology Co., Ltd.	58

180046-99-5(1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE)Related Search:

PYRROLIDINE-1-CARBOXYLIC ACID AMIDE 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE SDZ NKT 343 L-Alaninamide, 1-[[(2-nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)- 180046-99-5 C33H33N5O5 Highly selective human tachykinin NK1 receptor antagonist .