MRS 2279

MRS 2279 Structure
CAS No.
367909-40-8
Chemical Name:
MRS 2279
Synonyms
MRS 2279;MRS2279,MRS-2279;MRS 2279, CID: 5311301;[(1S,2R,4R)-4-[(2-chloro-6-methylaminopurin-9-yl)methyl]-2-(phosphonooxymethyl)cyclopentyl] dihydrogen phosphate;Bicyclo[3.1.0]hexane-1-methanol, 4-[2-chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)-, 1-(dihydrogen phosphate), (1R,2S,4S,5S)-;(1R*,2S*)-4-[2-Chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanoldihydrogenphosphateesterdiammoniumsalt
CBNumber:
CB3848748
Molecular Formula:
C13H18ClN5O8P2
Molecular Weight:
469.71
MOL File:
367909-40-8.mol
Modify Date:
2023/5/18 11:31:02

MRS 2279 Properties

storage temp. Desiccate at -20°C
form Powder
Water Solubility Soluble to 100 mM in water

MRS 2279 Chemical Properties,Uses,Production

Uses

MRS 2279 is a selective P2Y1 antagonist with high affinity and results in modulation of aggregation of blood platelets induced by ADP.

Biological Activity

Selective, high affinity competitive antagonist of the P2Y 1 receptor (K i = 2.5 nM; IC 50 = 51.6 nM). Fails to block nucleotide signaling at most other P2Y receptors (P2Y 2 , P2Y 4 , P2Y 6 , P2Y 11 and P2Y 12 ) and potently inhibits ADP-induced aggregation of human blood platelets in vitro (pK B = 8.05).

MRS 2279 Preparation Products And Raw materials

Raw materials

Preparation Products

MRS 2279 Suppliers

Global( 19)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23962 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Beijing Bolide Biotechnology Co., Ltd. 010-51653916 CHINA 6172 58 Inquiry
Shanghai Chaoyan Biotechnology Co., Ltd. 021-50840550 CHINA 6217 58 Inquiry
MRS 2279 (1R*,2S*)-4-[2-Chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanoldihydrogenphosphateesterdiammoniumsalt [(1S,2R,4R)-4-[(2-chloro-6-methylaminopurin-9-yl)methyl]-2-(phosphonooxymethyl)cyclopentyl] dihydrogen phosphate MRS 2279, CID: 5311301 Bicyclo[3.1.0]hexane-1-methanol, 4-[2-chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)-, 1-(dihydrogen phosphate), (1R,2S,4S,5S)- MRS2279,MRS-2279 367909-40-8 C13H18ClN5O8P22NH3 C13H18ClN5O8P2