ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >4-O-(Carboxymethyl)rifamycin
4-O-(Carboxymethyl)rifamycin
- CAS No.
- 13929-35-6
- Chemical Name:
- 4-O-(Carboxymethyl)rifamycin
- Synonyms
- C01848;Nacimycin;Nancimycin;Rifomycin B;NCI-145-604;Rifamycin B CRS;Rifamycin impurity A;Rifaximin EP Impurity B;Rifamycin EP Impurity A;Rifaximin impurity B (EP)
- CBNumber:
- CB3913884
- Molecular Formula:
- C39H49NO14
- Molecular Weight:
- 755.8
- MOL File:
- 13929-35-6.mol
- Modify Date:
- 2023/5/15 10:43:33
| Melting point | 300° (dec 160-164°) |
|---|---|
| alpha | D20 -11° (methanol) |
| Boiling point | 730.16°C (rough estimate) |
| Density | 1.2421 (rough estimate) |
| refractive index | 1.5350 (estimate) |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) |
| pka | 2.69±0.10(Predicted) |
| BRN | 604953 |
| Stability | Unstable in solution |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice (mg/kg): 2040 i.v., >3000 i.p., s.c., and orally (Sensi, 1964) |
|---|
4-O-(Carboxymethyl)rifamycin Chemical Properties,Uses,Production
Uses
A Rifamycin (R508200) derivative as antibacterial agent.
Purification Methods
Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]
4-O-(Carboxymethyl)rifamycin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 43)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-13602409664 | China | 3635 | 55 | Inquiry |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | China | 9911 | 50 | Inquiry |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016 | China | 9887 | 58 | Inquiry |
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Rifamycin impurity A
Rifaximin EP Impurity B
Rifamycin, 4-O-(carboxymethyl)-
4-O-(Carboxymethyl)rifamycin
Nacimycin
Nancimycin
NCI-145-604
Rifomycin B
C01848
Rifaximin impurity B (EP)
Rifaximin Impurity 2 (Rifaximin EP Impurity B)
Rifamycin EP Impurity A
Rifaximin EP Impurity B (Rifamycin B)
Rifamycin B CRS
Rifamycin Impurity 1(Rifamycin EP Impurity A)（Rifamycin B)
4-O-(Carboxymethyl)-Rifamycin (Rifaximin Impurity)
Rifaximin EP Impurity B（Rifamycin EP Impurity A）
13929-35-6
C39H49NO14
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals