O-(2,4-dinitrophenyl)hydroxylamine
- CAS No.
- 17508-17-7
- Chemical Name:
- O-(2,4-dinitrophenyl)hydroxylamine
- Synonyms
- 2,4-Dinitrophenylhydroxylamine;NSC 148499;2,4-NitrophenoxyaMine;2,4-DinitrophenoxyaMine;4-dinitrophenyl)hydroxylamine;1-aMinooxy-2,4-dinitro-benzene;O-(2,4-dinitrophenyl)hydroxylamine;HydroxylaMine,O-(2,4-dinitrophenyl)-;O-(2,4-Dinitrophenyl)hydroxylamine,98%;TIANFUCHEM--17508-17-7---O-(2,4-dinitrophenyl)hydroxylamine
- CBNumber:
- CB3922714
- Molecular Formula:
- C6H5N3O5
- Molecular Weight:
- 199.12
- MOL File:
- 17508-17-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:37
| Melting point | 112.5°C |
|---|---|
| Boiling point | 336.62°C (rough estimate) |
| Density | 1.6937 (rough estimate) |
| refractive index | 1.6910 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | solid |
| pka | -1.07±0.70(Predicted) |
| color | yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| TSCA | No | |||||||||
| HS Code | 29221990 | |||||||||
| NFPA 704 |
|
O-(2,4-dinitrophenyl)hydroxylamine price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D5103 | O-(2,4-Dinitrophenyl)hydroxylamine min. 97.0 % | 17508-17-7 | 1G | ₹2600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5103 | O-(2,4-Dinitrophenyl)hydroxylamine min. 97.0 % | 17508-17-7 | 5G | ₹7900 | 2022-05-26 | Buy |
O-(2,4-dinitrophenyl)hydroxylamine Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
O-(2,4-Dinitrophenyl)hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic r esidue with concomitant release of 2,4-dinitrophenol.
Preparation
To a stirred solution of 13.3 gm (0.1 mole) of t-butyl JV-hydroxycar-bamate and 5.6 gm (0.1 mole) of potassium hydroxide in 200 ml of absolute ethanol is added 20.2 gm (0.1 mole) of 2,4-dinitrochlorobenzene. The resultant deep red solution is stirred at room temperature for 1 hr; then enough glacial acetic acid is added dropwise to produce a light yellow solution. The solution is poured into 1.5 liters of cold water. The yellow oil which separates is gradually converted to crystals. The solid ?-butyl JV-(2,4-dinitrophenoxy)carbamate is separated, dried, and recrystallized from an ethyl acetate-hexane mixture to afford 16.4 gm (53%), m.p. 74-75°C. To 15 ml of trifluoroacetic acid is added 4 gm (0.0133 mole) of the i-butyl J/V-(2,4-dinitrophenoxy)carbamate. After the evolution of carbon dioxide has subsided, the solution is poured into 100 ml of ice water. The resultant oily layer crystallizes on standing to afford 2.5 gm (95%), m.p. 112°C (from ethanol).
Recently it was discovered that the alkylation of ethyl JV-hydroxy-carbamate under alkaline conditions, particularly in a DMF medium at 60°C in the presence of sodium bicarbonate, leads to the ultimate formation of O-alkylated hydroxylamines. On the other hand, at 80-85°C, the direct alkylation without the presence of a base ultimately leads to N-alkylhydrox-ylamines (see Table I) [59]. The reaction of ethylazidoformate with an alcohol, while perhaps hazardous, may have some merit (Eqs. 31-33). The overall yield, based on ethyl chloroformate, is said to be on the order of 60%.
O-(2,4-dinitrophenyl)hydroxylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SYNIX LABS | +919849178742 | Hyderabad, India | 108 | 58 | Inquiry |
| TRUE LABS | +91-9948900000 +91-8919325074 | Telangana, India | 161 | 58 | Inquiry |
| ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
| Innovative Labs | +91-9885794886 +91-9885794886 | Telangana, India | 219 | 58 | Inquiry |
| GOALSY PHARMA | +91-8247562464 +91-9885583385 | Hyderabad, India | 479 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
| Supplier | Advantage |
|---|---|
| SYNIX LABS | 58 |
| TRUE LABS | 58 |
| ALS INDIA LIFE SCIENCES | 58 |
| Innovative Labs | 58 |
| GOALSY PHARMA | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| A.J Chemicals | 58 |
| Capot Chemical Co.,Ltd. | 60 |
| Henan Tianfu Chemical Co.,Ltd. | 55 |