Echinocandin B

Echinocandin B Structure
CAS No.
54651-05-7
Chemical Name:
Echinocandin B
Synonyms
Ecb;A22082;A30912A;A 30912A;A-30912A;Nsc287461;1)-peptide;Aids008606;Aids-008606;A 30912 factor A
CBNumber:
CB41120280
Molecular Formula:
C52H81N7O16
Molecular Weight:
1060.24
MOL File:
54651-05-7.mol
MSDS File:
SDS
Modify Date:
2023/7/12 17:02:26

Echinocandin B Properties

Boiling point 1384.0±65.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A powder
pka 9.86±0.26(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501-P264-P280-P305+P351+P338-P337+P313P
NFPA 704
0
2 0

Echinocandin B Chemical Properties,Uses,Production

Uses

Echinocandin B is the major analogue of a family of lipopeptides isolated from several species of Aspergillus, reported in 1974. Echinocandin B is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

Definition

ChEBI: A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus nidulans var. echinulatus with specific anti-yeast activity.

Echinocandin B Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 58)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]] Aids008606 Aids-008606 Antibiotic A 22082 Antibiotic A 30912a Antibiotic sl 7810f Nsc287461 A 30912, A 22082, 7810, SL 7810F 1)-peptide A 30912 factor A Echinocandin B Impurity [1(Z,Z),6(2alpha,3beta,4beta)]-(4R,5R)-4,5-Dihydroxy-N2-(1-oxo-9,12-octadecadienyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-3-hydroxy-4-methyl-L-proline cyclic (6→1)-peptide Anidulafungin Intermediate Anidulafungin Echinocandin B Impurity Anidulafungin Impurity 10 (Echinocandin B) (9Z,12Z)-N-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-23-((1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6,20-bis((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)octadeca-9,12-dienamide Ecb A 30912A A22082 A30912A A-30912A 54651-05-7 C52H81N7O16