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O-Desmethyl Metoprolol

O-Desmethyl Metoprolol Structure
CAS No.
62572-94-5
Chemical Name:
O-Desmethyl Metoprolol
Synonyms
H 105/22;SL 80-008;SL 80-0088;Metoprolol-8;Betaxolol-001;Betalol impurity;O-demethylmetoprolo;Metoprolol-EP-Imp-H;Betaxolol Impurity 1;Betaxolol Impurity B
CBNumber:
CB41176641
Molecular Formula:
C14H23NO3
Molecular Weight:
253.34
MOL File:
62572-94-5.mol
Modify Date:
2023/6/8 9:02:50
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O-Desmethyl Metoprolol Properties

Melting point 70-720C
Boiling point 424.6±40.0 °C(Predicted)
Density 1.085±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka 13.88±0.20(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 intravenous in dog: 150mg/kg
NFPA 704
0
2 0

O-Desmethyl Metoprolol Chemical Properties,Uses,Production

Description

O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol . It is formed by metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6 in vivo.

Chemical Properties

Off-White Solid

Uses

O-Desmethyl Metoprolol (Metoprolol EP Impurity H) is a metabolite of Metoprolol.

O-Desmethyl Metoprolol Preparation Products And Raw materials

Raw materials

Preparation Products

O-Desmethyl Metoprolol Suppliers

Global( 93)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Orgamine Chemicals(I) Pvt Ltd +91-9820080281 +91-9820080281 Maharashtra, India 451 58 Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
Besil Chem LLP +91-7760252666 +91-9880731835 Bangalore, India 163 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
JSK Chemical 98797 67970 Gujarat, India 291 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Refsyn Biosciences Pvt., Ltd. 91-413-2200273 Tamil Nadu, India 226 58 Inquiry
Anant Pharmaceuticals Pvt. ltd +91 8550986868 Maharashtra, India 736 58 Inquiry
Supplier Advantage
Orgamine Chemicals(I) Pvt Ltd 58
GLP Pharma Standards 58
Besil Chem LLP 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
CLEARSYNTH LABS LTD. 58
JSK Chemical 58
Pharma Affiliates 58
Refsyn Biosciences Pvt., Ltd. 58
Anant Pharmaceuticals Pvt. ltd 58

62572-94-5(O-Desmethyl Metoprolol)Related Search:

3-[2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propoxy]-1-isopropylamino-2-propanol 1-(2-methoxyethyl)-4-nitrobenzene 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL H 128/80 rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
1,3-Bis[(1-Methylethyl)aMino]-2-propanol Dihydrochloride 1-(isopropylamino)-3-phenoxy-2-propanol 3-[4-(2-Methoxyethyl)phenoxy]- 2-Propanol, 1-[2-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]- p-(2-Methoxyethyl) phenol
1,1′-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol hydrochloride C-Desmethyl Metoprolol 4-Hydroxyphenethyl alcohol Metoprolol Impurity 1 Metoprolol EP IMpurity M
1-[4-(2-Methoxyethenyl)phenoxy]-3-[(1-Methylethyl)aMino]-2-propanol 1,1[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol (Mixture of diastereomers) LEVOBETAXOLOL
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(-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol (-O-Demethylmetoprolol 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol H 105/22 O-Desmethyl Metoprolol SL 80-008 O-demethylmetoprolo SL 80-0088 Metoprolol Tartrate EP IMpurity-H Metoprolol EP IMpurity H 1-(4-(2-hydroxyethyl)phenoxy) Metoprolol EP Impurity H (Betaxolol EP Impurity B) Metoprolol-EP-Imp-H Imp. H (EP):(2RS)-1-[4-(2-Hydroxyethyl)-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Metoprolol-8 Metoprolol impurity 6/Metoprolol EP Impurity H/O-Desmethyl Metoprolol/1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol Metoprolol Impurity 8 Betaxolol Impurity 1 1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Betaxolol-001 Betaxolol EP Impurity B Betaxolol Impurity 2(Betaxolol EP Impurity B) Metoprolol Impurity 8(Metoprolol EP Impurity H) (2RS)-1-[4-(2-Hydroxyethyl)phenoxy] Benzeneethanol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- 13/5000 Metoprolol tartrate impurity H Metoprolol EP Impurity H (O-Desmethyl Metoprolol) Betaxolol Impurity B Metoprolol Succinate EP Impurity H Betaxolol Hydrochloride EP Impurity B Betaxolol EP Impurity B (Metoprolol EP Impurity H) Betalol impurity Metoprolol EP Impurity 8 62572-94-5 1329613-82-5 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals