2-METHYLISONICOTINALDEHYDE
- CAS No.
- 63875-01-4
- Chemical Name:
- 2-METHYLISONICOTINALDEHYDE
- Synonyms
- 2-METHYL-4-FORMYLPYRIDINE;4-FORMYL-2-METHYLPYRIDINE;2-METHYLISONICOTINALDEHYDE;2-Methylisonicotinaldehyde 95%;2-Methyl-4-pyridinecarbaldehyde;2-METHYLPYRIDINE-4-CARBALDEHYDE;2-METHYLPYRIDINE-4-CARBOXALDEHYDE;2-Methyl-4-Pyridinecarboxaldehyde;4-Pyridinecarboxaldehyde,2-Methyl-;3-forMyl-2-Methylpyridine-4-carboxylic acid
- CBNumber:
- CB4126555
- Molecular Formula:
- C7H7NO
- Molecular Weight:
- 121.14
- MOL File:
- 63875-01-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/9 10:04:54
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
2-METHYLISONICOTINALDEHYDE Chemical Properties,Uses,Production
Uses
2-Methylisonicotinaldehyde belongs to the pyridine group of compounds and is used in the preparation of benzimidazoles and related analogues as sirtuin modulators and in the synthesis of other organic compounds.
Synthesis
2-Methylisonicotinaldehyde is synthesised using methanol as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of N,N-dimethyl-2-(2-methyl-4-pyridyl)ethenamine (6.4 g, 39 mmol) in methanol (25 ml) was added dropwise to a mixture of sodium periodate (25.2 g, 117 mmol) and methanol (25 ml) at room temperature..
The mixture was stirred at the same temperature for 1 hr..
The precipitates were filtered off, and the filtrate was concentrated..
The residue was combined with water and extracted with ethyl acetate..
The organic layer was washed with saturated brine and dried over magnesium sulfate..
The solvent was evaporated to give the titled compound (3.7 g, 78 percent).1H-NMR (CDCl3) δ: 2.68 (3H, s), 7.51 (1H, d, J = 4.9 Hz), 7.56 (1H, s), 8.76 (1H, d, J = 4.9 Hz), 10.05 (1H, s).
2-METHYLISONICOTINALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Terma Medicare India Pvt.,Ltd | +8613916485955 | Rajasthan, India | 150 | 58 | Inquiry |
| PRODIGIOUS LIFE SCIENCES | +91-9177472555 +91-9177472555 | Hyderabad, India | 236 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29889 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7621 | 58 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19447 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
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