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marcfortine A

marcfortine A Structure
CAS No.
75731-43-0
Chemical Name:
marcfortine A
Synonyms
UK 111866;marcfortine A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-
CBNumber:
CB41323193
Molecular Formula:
C28H35N3O4
Molecular Weight:
477.602
MOL File:
75731-43-0.mol
Modify Date:
2025/4/28 21:36:36
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marcfortine A Properties

Melting point 245 °C
Boiling point 660.6±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Methanol: soluble
form A solid
pka 12.05±0.60(Predicted)

marcfortine A Chemical Properties,Uses,Production

Description

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.

Uses

Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.

marcfortine A Preparation Products And Raw materials

Raw materials

Preparation Products

marcfortine A Suppliers

Global( 23)Suppliers
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BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32222 58 Inquiry
Aladdin Scientific United States 52924 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9803 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24719 58 Inquiry
Absin Bioscience Inc. 021-38015121-8802 CHINA 6208 58 Inquiry
Santa Cruz Biotechnology Inc 60936350 China 222068 58 Inquiry
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054 China 9522 58 Inquiry
Neobioscience Co., Ltd. 4006-800-892 CHINA 6207 58 Inquiry
Shanghai Weiyite Biotechnology Co., Ltd 15317051735 China 9736 58 Inquiry
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Absin Bioscience Inc. 58
Santa Cruz Biotechnology Inc 58
Shanghai Saikerui Biotechnology Co. , Ltd. 58
Neobioscience Co., Ltd. 58
Shanghai Weiyite Biotechnology Co., Ltd 58

75731-43-0(marcfortine A)Related Search:

C-[1-(4-METHOXY-PHENYL)-CYCLOPENTYL]-METHYLAMINE N-CYCLOPENTYL-N-METHYL-2-PIPERIDINEMETHANAMINE 2H-Indol-2-one,1,3-dihydro-6,7-dihydroxy-(9CI) ALPHA-PROPYLDOPACETAMIDE 1,1-DIMETHYL-2-PIPERIDIN-1-YL-ETHYLAMINE
CHEMBRDG-BB 4017497 CHEMBRDG-BB 4011370 [1-(3,4-DIMETHOXYPHENYL)CYCLOPENTYL]METHANAMINE CHEMBRDG-BB 4011371 2,5-Diazabicyclo[2.2.2]octane
2H-Pyrido[1,2-a]pyrazin-1(6H)-one,hexahydro-(6CI,8CI,9CI) (1S,4S)-2,5-DIAZABICYCLO(2.2.2)OCTANE marcfortine A
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marcfortine A UK 111866 Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)- 75731-43-0