imidazenil

imidazenil Structure
CAS No.
151271-08-8
Chemical Name:
imidazenil
Synonyms
imidazenil;6-(2-Bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide;4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide,6-(2-bromophenyl)-8-fluoro-;9-(2-bromophenyl)-12-fluoro-2,4,8-triazatricyclo[8.4.0.02,?]tetradeca-1(14),3,5,8,10,12-hexaene-5-carboxamide
CBNumber:
CB41338292
Molecular Formula:
C18H12BrFN4O
Molecular Weight:
399.22
MOL File:
151271-08-8.mol
Modify Date:
2024/9/13 19:17:58

imidazenil Properties

Boiling point 587.0±50.0 °C(Predicted)
Density 1.67±0.1 g/cm3(Predicted)
pka 15.37±0.40(Predicted)

imidazenil Chemical Properties,Uses,Production

Side effects

When taken by mouth: Ostarine is possibly unsafe. It might cause liver damage and other serious side effects such as heart attack.

Synthesis

The synthesis of imidazenil is as follows:
A mixture of 3 g (7.5 mmol) of 6-(2-bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 300 mL of methylene chloride and 2.25 g (10.8 mmol) of phosphorus pentachloride was stirred at room temperature for 2 hours. Ammonia gas was then introduced until the mixture was basic. After layering with 20 mL of concentrated aqueous ammonia, the mixture was stirred for 15 minutes. The methylene chloride was washed with water, dried and evaporated. The residue was crystallized from ethanol/water to yield 2.4 g of product having the above formula. A second crop of 0.4 g was obtained from the mother liquor for a total yield of 2.8 g. For analysis, a sample of the product was recrystallized from methylene chloride/ethanol and had m.p. 298°-299° C.
synthesis of imidazenil.png

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imidazenil 6-(2-Bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide,6-(2-bromophenyl)-8-fluoro- 9-(2-bromophenyl)-12-fluoro-2,4,8-triazatricyclo[8.4.0.02,?]tetradeca-1(14),3,5,8,10,12-hexaene-5-carboxamide 151271-08-8 C18H12BrFN4O