Reboxetine mesylate

Reboxetine mesylate Structure
CAS No.
71620-89-8
Chemical Name:
Reboxetine mesylate
Synonyms
Hulusu;Norebox;Prolift;REBOXETIN;Zinc00002284;Zinc00002275;Reboxetine mesylate;REBOXETINE(FORR&DONLY);Reboxetine mesylate base;Reboxetine mesylate USP/EP/BP
CBNumber:
CB4144618
Molecular Formula:
C19H23NO3
Molecular Weight:
313.4
MOL File:
71620-89-8.mol
Modify Date:
2023/5/4 17:34:41

Reboxetine mesylate Properties

Melting point 136-139 °C
Boiling point 443.7±30.0 °C(Predicted)
Density 1.113±0.06 g/cm3(Predicted)
storage temp. Desiccate at +4°C
solubility Chloroform (Slightly), Water (Slightly)
form Solid
pka 8.37±0.40(Predicted)
color Off-White to Pale Beige
CAS DataBase Reference 71620-89-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Reboxetine mesylate Chemical Properties,Uses,Production

Uses

Antidepressant (selective noradrenaline reuptake inhibitor).

brand name

Edronax (Pharmacia & Upjohn).

Biological Activity

Potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active, clinically used antidepressant.

Reboxetine mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine (R)-2-((S)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholine REBOXETINE(FORR&DONLY) REBOXETIN (2R)-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate (2R*)-2-[(alphaR*)-alpha-(o-Ethoxyphenoxy)benzyl]morpholine mesylate Reboxetine mesylate Zinc00002275 Zinc00002284 Reboxetine mesylate base Norebox Prolift Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel- Reboxetine mesylate USP/EP/BP Hulusu 71620-89-8 C20H27NO6S Inhibitors Adrenoceptors APIs Inhibitor Adrenoceptor