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12(S)-HPETE

12(S)-HPETE Structure
CAS No.
71774-10-2
Chemical Name:
12(S)-HPETE
Synonyms
12(S)-HPETE;12(S)HpETE,12(S) HpETE;ZIOZYRSDNLNNNJ-LQWMCKPYSA-N;12(S)-HpETE Lipid Maps MS Standard;12(S)-Hydroperoxy-eicosatetraenoic acid;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
CBNumber:
CB4154161
Molecular Formula:
C20H32O4
Molecular Weight:
336.47
MOL File:
71774-10-2.mol
Modify Date:
2023/6/8 9:03:09
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12(S)-HPETE Properties

Boiling point 518.0±50.0 °C(Predicted)
Density 1.013±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form Liquid.
pka 4.75±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

12(S)-HPETE Chemical Properties,Uses,Production

Description

12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.

Uses

12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO.

12(S)-HPETE Preparation Products And Raw materials

Raw materials

Preparation Products

12(S)-HPETE Suppliers

Global( 29)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BIOMOL INTERNATIONAL, LP (800) 942-0430 United States 1503 77 Inquiry
Alexis Corporation +41 61 926 8989 Switzerland 3599 74 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
CARBONE SCIENTIFIC CO.,LTD +44(0)870 486 8629 United Kingdom 6682 30 Inquiry
Beijing Zhijie Fangyuan Technology Co., Ltd. 010-82897201 15810200961 CHINA 6984 58 Inquiry
Xiamen Research Biotechnology Co., Ltd. 0592-6020891 18906011628 CHINA 6942 58 Inquiry
Beijing Taize Jiaye Technology Development Co., Ltd. 400-800-8151 CHINA 6050 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Boao Pike 010-57798038 15652371397 CHINA 6629 58 Inquiry
Shenzhen Xinbosheng Biological Technology Co., Ltd. 0755-26755892 CHINA 6164 58 Inquiry
Supplier Advantage
BIOMOL INTERNATIONAL, LP 77
Alexis Corporation 74
3B Scientific Corporation 47
CARBONE SCIENTIFIC CO.,LTD 30
Beijing Zhijie Fangyuan Technology Co., Ltd. 58
Xiamen Research Biotechnology Co., Ltd. 58
Beijing Taize Jiaye Technology Development Co., Ltd. 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Boao Pike 58
Shenzhen Xinbosheng Biological Technology Co., Ltd. 58

71774-10-2(12(S)-HPETE)Related Search:

12(S)-HPETE LIPID MAPS 12(S)-HPETE [1-14C] 12(R)-HPETE (+/-)12-HPETE 12(S)-HPETE
(+/-)12-HETE 12(S)-HETE 1,5-HEPTADIEN-4-OL 1.3.7-OCTATRIENE
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12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID 12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID 12(S)-HPETE (12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid (5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid (5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid 12(S)-Hydroperoxy-eicosatetraenoic acid (5Z,8Z,10Z,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid 12(S)-HpETE Lipid Maps MS Standard ZIOZYRSDNLNNNJ-LQWMCKPYSA-N 12(S)HpETE,12(S) HpETE 5,8,10,14-Eicosatetraenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z)- 71774-10-2