(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate

(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate Structure
CAS No.
681490-92-6
Chemical Name:
(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate
Synonyms
(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate;(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate;1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-methanesulfonate, (βR)-
CBNumber:
CB43154146
Molecular Formula:
C8H12ClN3O6S
Molecular Weight:
313.72
MOL File:
681490-92-6.mol
Modify Date:
2023/4/23 13:52:06

(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate Properties

Boiling point 608.3±65.0 °C(Predicted)
Density 1?+-.0.1 g/cm3(Predicted)
solubility Chloroform, DCM
form Solid
pka 12.77±0.29(Predicted)
color Off White

(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate Chemical Properties,Uses,Production

Uses

(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate Suppliers

Global( 6)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6038 71 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6650 58 Inquiry
Lynnchem 86-(0)29-85992781 17792393971 China 4587 58 Inquiry
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q China 20033 58 Inquiry
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016 China 9122 58 Inquiry
(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropylmethanesulfonate (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate 1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-methanesulfonate, (βR)- 681490-92-6 C8H12ClN3O6S