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ISOXABEN

ISOXABEN Structure
CAS No.
82558-50-7
Chemical Name:
ISOXABEN
Synonyms
el107;NA 8318;FLEXIDOR;ixoxaben;ISOXABEN;Isoaxben;benzamizole;ISOXABEN STANDARD;ISOXABEN PESTANAL;ISOXABEN PESTANAL, 250 MG
CBNumber:
CB4362249
Molecular Formula:
C18H24N2O4
Molecular Weight:
332.39
MOL File:
82558-50-7.mol
Modify Date:
2023/4/23 13:52:06

ISOXABEN Properties

Melting point 175-179 °C
Boiling point 469.52°C (rough estimate)
Density 1.2149 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. 0-6°C
pka 11.44±0.70(Predicted)
EPA Substance Registry System Isoxaben (82558-50-7)

SAFETY

Risk and Safety Statements

Hazard statements  H413
Precautionary statements  P273-P501
Hazard Codes  Xn
Risk Statements  53-40
Safety Statements  61-36
WGK Germany  3
RTECS  CV4370300

ISOXABEN price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 36138 Isoxaben PESTANAL?, analytical standard 82558-50-7 100MG ₹4784.65 2022-06-14 Buy
Sigma-Aldrich(India) 36138 Isoxaben PESTANAL?, analytical standard 82558-50-7 100MG ₹4784.65 2022-06-14 Buy
Product number Packaging Price Buy
36138 100MG ₹4784.65 Buy
36138 100MG ₹4784.65 Buy

ISOXABEN Chemical Properties,Uses,Production

Uses

Isoxaben is used primarily for preemergence control of annual broadleaf weeds. Isoxaben is usually applied to soil either with light incorporation or before application of water (at least 0.5 in) within 3 weeks. As is the case with DCB, it is most effective on weed seedlings before emergence.

Definition

ChEBI: A benzamide obtained by formal condensation of the carboxy group of 2,6-dimethoxybenzoic acid and the amino group of 3-(3-methylpentan-3-yl)-1,2-oxazol-5-amine.

Pharmacology

Although isoxaben is readily absorbed through the root system, foliar absorption and translocation is poor. Reduced root absorption may be partly responsible for the tolerance of some dicot species to isoxaben, although differences in the site of action appears to be the major contributing factor in tolerance (15).Up to 50% of absorbed isoxaben is metabolized within 6 days following root application (16). Differences in metabolism cannot explain the selectivity of isoxaben between tolerant and susceptible species (17,18). Metabolism of isoxaben involves hydroxylation of the propyl side group and glucosylation. 2,6-dimethoxybenzamide is found as a minor metabolite (19). Isoxaben prevents the germination and growth of seedlings before emergence, by inhibiting cell division.
The primary mode of action of isoxaben is inhibition of cellulose biosynthesis, although the exact mechanism is unclear. Isoxaben has been shown to specifically inhibit the incorporation of glucose into the acid-insoluble fraction (presumed to be cellulose) of the cell walls of Arabidopsis thaliana (20) and soybean cell suspension cultures (21). This herbicide also disrupts cell plate formation in root tips (22) and tobacco suspension cells (23). Isoxaben affects a different site of action compared with DCB, as it inhibits cytokinesis at an earlier stage in which callose is deposited at the developing cell plate (23). There are no known cases of resistance to this herbicide.

Metabolism

Isoxaben is adsorbed strongly to soil and therefore has very limited mobility. Volatilization and photodegradation of isoxaben is negligible when applied to soil. Isoxaben is mainly degraded by soil organisms and has an average half-life of 1 to 2 months in the field, providing an average of 5 to 6 months of weed control at normal rates of application (19).

ISOXABEN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 79)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 23053 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Shanghai klamar Reagent Co., LTD 4001650900 13817534909 China 10709 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
2,6-dimethoxy-n-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)-benzamid 2,6-dimethoxy-n-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)benzamide benzamizole el107 n-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)-2,6-dimethoxybenzamide ixoxaben N-(3-(1-ethyl-1-methylpropyl)-1,2-oxazol-5-yl)-2,6-dimethoxybenzamide N-(3-(1-ethyl-1-methylpropyl)-5-isoxazoyl)-2,6-dimethoxybenzamide ISOXABEN PESTANAL ISOXABEN PESTANAL, 250 MG FLEXIDOR ISOXABEN ANALYTICAL STANDARD Benzamide, N-3-(1-ethyl-1-methylpropyl)-5-isoxazolyl-2,6-dimethoxy- ISOXABEN STANDARD N-[3-(1-Ethyl-1-methylpropyl)isoxazol-5-yl]-2,6-dimethoxybenzamide ISOXABEN Isoaxben Isoxaben @100 μg/mL in MeOH Isoxaben@1000 μg/mL in Methanol Isoxaben Solution in Methanol, 100μg/mL NA 8318 Methylprednisolone Impurity 40 2,6-Dimethoxy-N-[3-(3-methyl-3-pentyl)-5-isoxazolyl]benzamide EL 107|||NA 8318|||Isoxaben 82558-50-7 82558-40-7 Alpha sort Alphabetic AmidePesticides&Metabolites Herbicides H-MAnalytical Standards I Pesticides&Metabolites