Testolactone

Testolactone Structure
CAS No.
968-93-4
Chemical Name:
Testolactone
Synonyms
teslak;teslac;teolit;sq9538;nsc-12173;NSC-23759;fludestrin;testolacton;TESTOLACTONE;Δ1-Testolactone
CBNumber:
CB4371689
Molecular Formula:
C19H24O3
Molecular Weight:
300.39
MOL File:
968-93-4.mol
Modify Date:
2023/11/1 18:37:15

Testolactone Properties

Melting point 218-219°
alpha D23 -45.6° (c = 1.24 in chloroform)
Boiling point 482.0±45.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 968-93-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

HS Code  2937290000

Testolactone Chemical Properties,Uses,Production

Uses

Testolactone USP (Teslac) is used to treat Breast cancer.

General Description

Testolactone, 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acidΔ-lactone (Teslac),was originally synthesized as a possible anabolic steroid,considering its structural similarity to testosterone. The keystructural difference from anabolic steroids is the D-ring lactone instead of the typical cyclopentyl ring. Althoughconsidered in many texts an androgen or anabolic steroid (itis a Schedule III drug because of its classification as an anabolicsteroid), testolactone lacks androgenic effects in vivo.Its action is believed to be caused by irreversible inhibitionof aromatase. It is a relatively weak inhibitor of aromatase,but the irreversible nature of the inhibition can lead to prolongedeffects. Its relatively weak inhibition of aromataseand its undesirable dosage schedule (5×50-mg tabletsq.i.d.) give this older agent only limited use in breast cancertreatment because of better available options.

Testolactone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +8613288715578 China 12455 58 Inquiry
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CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
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Chongqing Botao Biotechnology Co., LTD 15223382610 15223382610 China 1831 58 Inquiry
delta(1)-dehydrotestololactone delta(1)-testolactone delta-1-testololactone d-homo-17a-oxaandrosta-1,4-diene-3,17-dione epropionicaciddelta-lactone fludestrin nsc-12173 sq9538 teolit teslac teslak testolacton 17a-Oxa-D-homoandrosta-1,4-diene-3,17-dione NSC-23759 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone 1,2-didehydrotestololactone Testolactone CIII (125 mg) (4aS,4bR,10aR,10bS,12aS)-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-diMethyl-2H-phenanthro[2,1-b]pyran-2,8(4bH)-dione 13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic Acid δ-Lactone 17a-Oxa-D-hoMo-1,4-androstadiene-3,17-dione Δ1-Testolactone Δ1-Testololactone Testolactone ketone (4as,4br,10ar,10bs,12ar)-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3h-naphtho[6,5-f]chromene-2,8-dione TESTOLACTONE 1,2,3,4,4a,4b,7,9,10,10a-decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthren 1,2-dehydrotestololactone 1,2-didehydro-testololacton 17alpha-oxo-d-homo-1,4-androstadiene-3,17-dione 17-secoandrosta-1,4-dien-17-oicacid,13-hydroxy-3-oxo-1delta-lactone 1-dehydrotestololactone delta(1)-dehydrotestolactone 2H-Phenanthro[2,1-b]pyran-2,8(4bH)-dione, 3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-, (4aS,4bR,10aR,10bS,12aS)- Testolactone CIII (1645006) 968-93-4 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Steroids