Testolactone

CAS No.: 968-93-4

Chemical Name:: Testolactone

Synonyms: teslak;teslac;teolit;sq9538;nsc-12173;NSC-23759;fludestrin;testolacton;TESTOLACTONE;Δ1-Testolactone

CBNumber:: CB4371689

Molecular Formula:: C19H24O3

Molecular Weight:: 300.39

MOL File:: 968-93-4.mol

Modify Date:: 2023/11/1 18:37:15

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Testolactone Properties

Melting point	218-219°
alpha	D23 -45.6° (c = 1.24 in chloroform)
Boiling point	482.0±45.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Solid
color	White to Off-White
CAS DataBase Reference	968-93-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

HS Code	2937290000
Hazardous Substances Data	968-93-4(Hazardous Substances Data)

Testolactone Chemical Properties,Uses,Production

Uses

Testolactone USP (Teslac) is used to treat Breast cancer.

General Description

Testolactone, 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acidΔ-lactone (Teslac),was originally synthesized as a possible anabolic steroid,considering its structural similarity to testosterone. The keystructural difference from anabolic steroids is the D-ring lactone instead of the typical cyclopentyl ring. Althoughconsidered in many texts an androgen or anabolic steroid (itis a Schedule III drug because of its classification as an anabolicsteroid), testolactone lacks androgenic effects in vivo.Its action is believed to be caused by irreversible inhibitionof aromatase. It is a relatively weak inhibitor of aromatase,but the irreversible nature of the inhibition can lead to prolongedeffects. Its relatively weak inhibition of aromataseand its undesirable dosage schedule (5×50-mg tabletsq.i.d.) give this older agent only limited use in breast cancertreatment because of better available options.

Testolactone Preparation Products And Raw materials

Raw materials

BROWNSUGAR CORN STEEP LIQUOR

Preparation Products

Testolactone Suppliers

Global( 65)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	China	12809	58	Inquiry
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	China	615	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	China	34563	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24727	58	Inquiry
Shandong Hanjiang Chemical Co., Ltd	+86-0533-2066820 +8618369939125	China	1009	58	Inquiry
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	+8618950047208	China	43416	58	Inquiry
nanjing	13376082704 13376082704	China	2907	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58
Shandong Hanjiang Chemical Co., Ltd	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	58
nanjing	58

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delta(1)-dehydrotestololactone delta(1)-testolactone delta-1-testololactone d-homo-17a-oxaandrosta-1,4-diene-3,17-dione epropionicaciddelta-lactone fludestrin nsc-12173 sq9538 teolit teslac teslak testolacton 17a-Oxa-D-homoandrosta-1,4-diene-3,17-dione NSC-23759 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone 1,2-didehydrotestololactone Testolactone CIII (125 mg) (4aS,4bR,10aR,10bS,12aS)-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-diMethyl-2H-phenanthro[2,1-b]pyran-2,8(4bH)-dione 13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic Acid δ-Lactone 17a-Oxa-D-hoMo-1,4-androstadiene-3,17-dione Δ1-Testolactone Δ1-Testololactone Testolactone ketone (4as,4br,10ar,10bs,12ar)-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3h-naphtho[6,5-f]chromene-2,8-dione TESTOLACTONE 1,2,3,4,4a,4b,7,9,10,10a-decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthren 1,2-dehydrotestololactone 1,2-didehydro-testololacton 17alpha-oxo-d-homo-1,4-androstadiene-3,17-dione 17-secoandrosta-1,4-dien-17-oicacid,13-hydroxy-3-oxo-1delta-lactone 1-dehydrotestololactone delta(1)-dehydrotestolactone 2H-Phenanthro[2,1-b]pyran-2,8(4bH)-dione, 3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-, (4aS,4bR,10aR,10bS,12aS)- Testolactone CIII (1645006) 968-93-4 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Steroids