ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyran compounds >TRIOXSALEN
TRIOXSALEN
- CAS No.
- 3902-71-4
- Chemical Name:
- TRIOXSALEN
- Synonyms
- LACTONE;NSC-71047;Trioxalen;Trioxsale;Trixsalen;rioxsalen;TRIOXSALEN;TRISORALEN;Elder 8011;TRIOXSALIN
- CBNumber:
- CB1363250
- Molecular Formula:
- C14H12O3
- Molecular Weight:
- 228.24
- MOL File:
- 3902-71-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/20 16:43:00
| Melting point | 229-231 °C(lit.) |
|---|---|
| Boiling point | 310.05°C (rough estimate) |
| Density | 1.2196 (rough estimate) |
| refractive index | 1.5557 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | powder |
| color | white |
| Merck | 14,9735 |
| BRN | 221723 |
| CAS DataBase Reference | 3902-71-4 |
| IARC | 3 (Vol. 40, Sup 7) 1987 |
| EPA Substance Registry System | 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl- (3902-71-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H312+H332-H314-H341 | |||||||||
| Precautionary statements | P202-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-40 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 1759 8/PG 1 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | LV1576000 | |||||||||
| F | 8-10 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29322985 | |||||||||
| NFPA 704 |
|
TRIOXSALEN price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T6137 | Trioxsalen ≥98% (HPLC), powder | 3902-71-4 | 100MG | ₹10240.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T6137 | Trioxsalen ≥98% (HPLC), powder | 3902-71-4 | 500MG | ₹33308.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T6137 | Trioxsalen ≥98% (HPLC), powder | 3902-71-4 | 1G | ₹52035.78 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T2267 | Trioxsalen | 3902-71-4 | 1G | ₹5900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T2267 | Trioxsalen | 3902-71-4 | 5G | ₹16300 | 2022-05-26 | Buy |
TRIOXSALEN Chemical Properties,Uses,Production
Chemical Properties
White to slightly beige crystalline powder
Uses
Trioxsalen has been used:
- to induce small deletion mutations in worms
- in combination with ultraviolet A (UVA)
- to induce interstrand crosslinks (ICLs) in DNA
- for the preparation and photoactivation of trimethyl psoralen
Indications
Trioxsalen (Trisoralen) followed by UVA exposure is used to repigment vitiliginous areas and in photochemotherapy.
Definition
ChEBI: 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phot therapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermi .
Purification Methods
Purify trioxsalen by recrystallisation from CHCl3. If too impure, it is fractionally crystallised from CHCl3/pet ether (b 30-60o) using Norit and finally crystallised from CHCl3 alone to give colourless prisms, m 234.5-235o. It is a photosensitiser so it should be stored in the dark. [UV: Kaufmann J Org Chem 26 117 1961, Baeme et al. J Chem Soc 2976 1949, Beilstein 19/4 V 472.]
TRIOXSALEN Preparation Products And Raw materials
Raw materials
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Global( 122)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JIVICHEM SYNTHESIS PVT LTD | +91-7028392790 +91-7028392790 | Maharashtra, India | 337 | 58 | Inquiry |
| Himpharm | +91-9816648055 +91-9816664455 | Himachal Pradesh, India | 29 | 58 | Inquiry |
| Shimoga Chemicals | +91-9423565742 +91-9423565743 | Maharashtra, India | 10 | 58 | Inquiry |
| Namiex Chemicals Private Limited | +91-1862225256 +91-9988625256 | Punjab, India | 13 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| Odyssey Organics Pvt. Ltd. | +91 (251) 269-1342 | New Delhi, India | 7 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| JIVICHEM SYNTHESIS PVT LTD | 58 |
| Himpharm | 58 |
| Shimoga Chemicals | 58 |
| Namiex Chemicals Private Limited | 58 |
| OCEAN TRADING CORPORATION | 58 |
| Medilink Pharmachem | 50 |
| Odyssey Organics Pvt. Ltd. | 50 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
3902-71-4(TRIOXSALEN)Related Search:
Psoralen
TRIOXSALEN
3-(HYDROXYMETHYL)-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
PSORALEN-C 6 CEP
Trioxsalen, 4-Aminomethyl-, HCl
3-CHLOROMETHYL-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
PSORALEN-C 2 CEP
3-(6-HYDROXYHEXYL)METHYL-2,5,9-TRIMETHYL-7H-FURO[3,2-G]-[1]BENZOPYRAN-7-ONE
3-(2-HYDROXY-ETHOXYMETHYL)-2,5,9-TRIMETHYL-FURO[3,2-G]CHROMEN-7-ONE
TRIOXSALEN(RG)
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TRISORALEN
TRIOXSALEN
TRIOXYSALEN
2',4,8-Trimethylpsoralen
2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one
2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one
2,5,9-TRIMETHYL-FURO[3,2-G]BENZOPYRAN-7-ONE
2,5,9-TRIMETHYL-FUROL[3,2-G]BENZOPYRAN-7-ONE
2,5,9-TRIMETHYLPSORALEN
TRIOXSALEN, FOR FLUORESCENCE
4,5',8-Trimethylpsoralen, 97.50%
TRIOXSALEN,USP
TRIOXSALEN (4,5,8-TRIMETHYLPSORALEN)
2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one, 4,5μ,8-Trimethylpsoralen, TMP, Trisoralen
4,2',8-Trimethylpsoralen
4,5',8-Trimethylpsoralen,97.5%
4,5,8-Trimethylpsoralen ,99%
Trioxsalen (200 mg)
TMP
2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one
4,5',8-Trimethylpsoralen
Trisoralen
2’,4,8-trimethylpsoralen
2-g)(1)benzopyran-7-one,2,5,9-trimethyl-7h-furo(
2-g][1]benzopyran-7-one,2,5,9-trimethyl-7h-furo[
4,5',8-Trimethylpsoralene
5-Benzofuranacrylic acid, 6-hydroxy-beta,2,7-trimethyl-, delta-lactone
6-hydroxy-beta,2,7-trimethyl-5-benzofuranacrylicacidgamma-lactone
7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-
Benzofuranacrylic acid,6-hydroxy-b,2,7-trimethyl-,
Elder 8011
LACTONE
NSC-71047
psoralen,4,5’,8-trimethyl-
Trimethylpsoralen
Trioxalen
Trioxsale
TRIOXSALIN
Trixsalen
4,5',8-TRIMETHYLPSORALEN
4,5,8-TRIMETHYLPSORALEN
)-7-Cyano-17-hydroxy-3-oxo-pregna-4,9(11)-diene-21-carboxylic acid &gamma
3,13-Dihydroxy-13,17-secoandrost-5-en-17-oic Acid &delta
2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic acid &gamma
5-O-(1-Methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-D-ribonic Acid &gamma
11,12-Dihydro-11-hydroxyretinoic Acid &delta
17-Hydroxy-3-oxo-17&alpha
-pregna-4,20-diene-21-carboxylic Acid &gamma
Homogentisic Acid &gamma
N-Boc L-Serine b-Lactone ([(3S)-2-oxo-3-oxetanyl]-1,1-dimethylethyl Ester Carbamic Acid, |N-(tert-Butoxycarbonyl)-L-serine ß
4-tert-Butyldimethylsilyl-6&rsquo
-carboxy-5&rsquo
-hydroxy Simvastatin &gamma
rioxsalen
TRIOXSALEN ISO 9001：2015 REACH
TrioxsalenQ: What is
Trioxsalen Q: What is the CAS Number of
Trioxsalen Q: What is the storage condition of
Trioxsalen Q: What are the applications of
Trioxsalen
2,5,9-trimethylfuro[3,2-g]chromen-7-one
Trioxsalen (1693009)
16-Deacetylfusidic Acid &gamma
2,5,9-trimethyl-7-furo[3,2-g][1]benzopyranone
6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid &gamma