tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
- CAS No.
- 1118767-16-0
- Chemical Name:
- tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
- Synonyms
- tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu;Semaglutide side chain;(S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid;Side chain;Carbaryl Impurity 3;Egf(a) analogue-13C4;Somaluptide side chain;Semaglutide impurity 22;tBuO-Ste-Glu(AEEA-AEEA)-OtBu;intermediates of semaglutide
- CBNumber:
- CB43975343
- Molecular Formula:
- C43H79N3O13
- Molecular Weight:
- 846.1
- MOL File:
- 1118767-16-0.mol
- Modify Date:
- 2024/4/17 13:12:23
| Boiling point | 940.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.079±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place, Sealed in dry, Store in freezer, under -20°C |
| pka | 3.39±0.10(Predicted) |
| InChIKey | YZUXNRZPWYRMGH-DHUJRADRSA-N |
| SMILES | C(O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Chemical Properties,Uses,Production
Description
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is the 18-carbon fatty acid side chain of somatostatin, which contributes to an increased affinity for albumin (approximately 5-6 fold). Somalutide is a glucagon-like peptide-1 (GLP-1) analogue with hypoglycaemic properties.
Uses
(S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.
Application
OLED intermediates, Pharmaceutical Raw Intermediates, Fine Chemical Intermediate
Definition
TBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is also known as Semaglutide Side Chain. An 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy.
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 186)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | China | 59 | 58 | Inquiry |
| SyncoZymes (Shanghai) Co., Ltd., | +86-021-68187180-811 +86-13681683526 | China | 188 | 58 | Inquiry |
| Chemtour Biotech Co., Ltd | +8617327281506 | China | 1460 | 58 | Inquiry |
| Seasons Biotechnology Co., Ltd. | +86-0576-89232655 +86-13566878689 | China | 47 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20327 | 58 | Inquiry |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 | China | 562 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
| Shanghai Worldyang Chemical Co.,Ltd. | ,+86-21-56795779; +8613651600618 | China | 1080 | 58 | Inquiry |
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1118767-16-0(tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu)Related Search:
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(S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid
Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH
Side chain
Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OHu
Egf(a) analogue-13C4
3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) ester, (22S)-
tBuO-Ste-Glu(AEEA-AEEA)-OtBu
Octa(OtBu)-Glu(AEEA-AEEA-OH)-OtBu
Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH
Octadecane(OtBu)-Glu( α -OtBu)-AEEA-AEEA-
OH
(S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid
Semaglutide side chain
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
TBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu/ Semaglutide Side Chain
Somaluptide side chain
intermediates of semaglutide
PEG2-PEG2-(γ-Glu-tBu)-17-carboxyheptadecanoyl-tBu
tBuO-Ste-E(AEEA-AEEA-OH)OtBu
(S)-22-(tert-butoxycarbonyl)-30,30-dimethyl-10,19,24,28-tetraoxo-3,6,12,15,29-pentaoxa-9,18,23-triazahentriacontanoic acid
Carbaryl Impurity 3
tBuO-Ste-γGlu(OtBu)-AEEA- AEEA-OH
tBuO-Ste-rGlu(OtBu)-AEEA-AEEA-OH
3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-,41-(1,1-dimethylethyl) ester
2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(18-tert-butoxy-18-oxo-octadecanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid
Semaglutide impurity 22
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu (DMF solution)
Semaglutide side chain-tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu
1118767-16-0
C43H79N3O13