ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >FMOC-amino acid >Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-8-amino-3,6-dioxaoctanoic acid
- CAS No.
- 166108-71-0
- Chemical Name:
- Fmoc-8-amino-3,6-dioxaoctanoic acid
- Synonyms
- FMOC-AEEA-OH;FMOC-AEEA;FMOC-AEEAC-OH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid;FMoc-NH-PEG2-CH2COOH;FMOC-AEEAC;FMOC-8-AMINO-3,6-DIOXAOCTANOIC ACID;Fmoc-Ado-OH;N-formylglycine t-butylester;9-FLUORENYLMETHOXYCARBONYL-8-AMINO-3,6-DIOXAOCTANOIC ACID
- CBNumber:
- CB2169923
- Molecular Formula:
- C21H23NO6
- Molecular Weight:
- 385.41
- MOL File:
- 166108-71-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/18 8:51:57
| Melting point | 90-92℃ |
|---|---|
| Boiling point | 631.4±45.0 °C(Predicted) |
| Density | 1.265±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 3.40±0.10(Predicted) |
| form | Crystalline Powder |
| color | White |
| InChI | InChI=1S/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24) |
| InChIKey | XQPYRJIMPDBGRW-UHFFFAOYSA-N |
| SMILES | C(O)(=O)COCCOCCNC(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2 |
| CAS DataBase Reference | 166108-71-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P271-P261-P280 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
Fmoc-8-amino-3,6-dioxaoctanoic acid price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 95003 | {2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid ≥95.0% (HPLC) | 166108-71-0 | 500MG | ₹19506.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.51037 | Fmoc-NH-(PEG)-COOH (9 atoms) Novabiochem? | 166108-71-0 | 1G | ₹30870 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F0719 | 8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoic Acid | 166108-71-0 | 200MG | ₹4200 | 2022-05-26 | Buy |
| ALFA India | ALF-H63641-MD | (2-[2-(Fmoc-amino)ethoxy]ethoxy)acetic acid, 95% | 166108-71-0 | 250mg | ₹6824 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F0719 | 8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoic Acid | 166108-71-0 | 1G | ₹14800 | 2022-05-26 | Buy |
Fmoc-8-amino-3,6-dioxaoctanoic acid Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
Hydrophillic spacer group.
Application
Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker for the synthesis of antibody-drug couplings (ADCs). It is also a PEG linker for the synthesis of PROTAC. It is widely used in drug delivery systems as it is mainly used to enhance the solubility or targeting of drugs and improve their bioavailability.
Fmoc-8-amino-3,6-dioxaoctanoic acid Preparation Products And Raw materials
Raw materials
Phthalimide
Triethylene glycol
Hydrazinium hydroxide solution
N,N-Dimethylformamide
Potassium carbonate
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Global( 440)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| NSJ Prayog Life Sciences Private Limited | +91-6281747900 +91-6281747900 | Hyderabad, India | 76 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Gagri Global IT Services Pvt. Ltd. | +91-40-27170174, | Telangana, India | 1321 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Siddhi Specialities | 91-0-9742033800 | Bangalore, India | 162 | 58 | Inquiry |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | China | 1356 | 58 | Inquiry |
| Shandong Hengshannuode Pharmaceutical Technology Co., Ltd. | +8615065888978 | China | 92 | 58 | Inquiry |
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Fmoc-8-amino-3,6-dioxaoctanoic acid,
Fmoc-AEEA
Fmoc-PEG2-acetic acid
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid≥ 99% (HPLC)
Fmoc-NH-(PEG)-COOH (9 atoms) Novabiochem
1-(9H-Fluoren-9-yl)-3-oxo-2,7,1-trioxa-4-azadodecan-12-oic acid
8-(FMOC-AMINO)-3,6-DIOXA-OCTANOIC ACID
8-FLUORENYLMETHOXYCARBONYLAMINO-3,6-DIOXAOCTANOIC ACID
8-(9-FLUORENYLMETHOXYCARBONYL-AMINO)-3,6-DIOXA-OCTANOIC ACID
8-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID
FMOC-O2OC-OH
FMOC-MINI-PEG(TM)
FMOC-[2-(2-AMINO-ETHOXY)-ETHOXY]-ACETIC ACID
8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoicacid,{2-[2-(Fmoc-amino)ethoxy]ethoxy}aceticacid,1-(9H-Fuoren
8-(9-FLUOROENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID
Fmoc-PEG2- CH2COOH (Fmoc-AEEA)
8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoic Acid
8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid, {2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, 1-(9H-Fuoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid, Fmoc-Ado, Fmoc-AEEA
2-(2-(2-(((9H-fluoren-9-yl)Methoxy)carbonyl)ethoxy)ethoxy)acetic acid
8-(Fmoc-amino)-3,6-dioxa-n-octanoic Acid
[2-[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy]ethoxy]acetic Acid
[2-[2-[(Fmoc-amino)ethoxy]ethoxy]acetic Acid
{2-[2-(FMoc-aMino)-ethoxy]-ethoxy}-acetic acid, 8-(FMoc-aMino)-3,6-dioxa-octanoic acid, FMoc-Adoa-OH
[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid ,98.5%
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid,8-(Fmoc-amino)-3,6-dioxaoctanoic acid
FMoc-2-(2- (2-aMinoethoxy)ethoxy)
acetic acid
RARECHEM EM WB 0032
1-(9H-FUOREN-9-YL)-3-OXO-2,7,10-TRIOXA-4-AZADODECAN-12-OIC ACID
(2-[2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-ETHOXY]-ETHOXY)-ACETIC ACID
(2-[2-(FMOC-AMINO)-ETHOXY]-ETHOXY)-ACETIC ACID
6-dioxaoctanoic acid
Fmoc-8-amino-3
Fmoc-NH-(PEG)-COOH (9 atoms)
MOC-AEEAC-OH
[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid, 97.0%
2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]ethoxy}acetic acid
Fmoc-NH-PEG2-CH2COOH,Fmoc-AEEA
Fmoc-AEEA
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid
8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoicAcid>
3,6,11-Trioxa-9-azadodecanoic acid, 12-(9H-fluoren-9-yl)-10-oxo-
Fmoc-AEEA/Fmoc-Mini-PEG
2-[2-(Fmoc-amino)ethoxy]ethoxy]aceticaci
8-(Fmoc-amino)-3,6-dioxa-n-octanoic Acid
[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid USP/EP/BP
9-FLUORENYLMETHOXYCARBONYL-8-AMINO-3,6-DIOXAOCTANOIC ACID
FMOC-AEEA
FMOC-AEEAC-OH
FMOC-8-AMINO-3,6-DIOXAOCTANOIC ACID
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid
FMOC-AEEA-OH
FMoc-NH-PEG2-CH2COOH
FMOC-AEEAC
N-formylglycine t-butylester
Fmoc-Ado-OH
Fmoc-N-Amido-PEG2-CH2COOH
Fmoc-N-amido-PEG2-acetic acid
Fluorene methoxycarbonyl dipolyethylene glycol acetic acid
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH)
166108-71-0
Specialty Synthesis
Peptide PEGylation