(-)-LUPININE
- CAS No.
- 486-70-4
- Chemical Name:
- (-)-LUPININE
- Synonyms
- LUPININE;LUPININ;(-)-LUPININE;(–)-Lupinine;LUPININE HCL(P);(-)-Lupinine,97%;Lupinine, 10 mM in DMSO;OCTAHYDRO-1H-QUINOLIZIN-1-METHANOL;[(1R,9aR)-quinolizidin-1-yl]methanol;TIANFU-CHEM CAS NO.486-70-4 (-)-LUPININE
- CBNumber:
- CB4409360
- Molecular Formula:
- C10H19NO
- Molecular Weight:
- 169.26
- MOL File:
- 486-70-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/19 23:02:33
| Melting point | 62-65°C |
|---|---|
| Boiling point | 160-164°C 4mm |
| alpha | D26 -25.9° (c = 3 in water); D28 -21° (c = 9.5 in alcohol) |
| Density | 0.9660 (rough estimate) |
| refractive index | 1.4610 (estimate) |
| Flash point | 160-164°C/4mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Very Dark Orange |
| pka | 14.90±0.10(Predicted) |
| color | Light yellow to yellow |
| Merck | 14,5609 |
| BRN | 80447 |
| Stability | Hygroscopic |
| LogP | 1.290 (est) |
| CAS DataBase Reference | 486-70-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2H-quinolizine-1-methanol, octahydro-, (1r-trans)-(486-70-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H332 | |||||||||
| Precautionary statements | P261-P280h-P301+P312a-P304+P340-P321-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 20/21/22-41 | |||||||||
| Safety Statements | 22-36/37-39-26 | |||||||||
| RIDADR | 1544 | |||||||||
| RTECS | OK5802000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
(-)-LUPININE Chemical Properties,Uses,Production
Chemical Properties
Crystalline solid, obtained as orthorhombic prisms from acetone; melts at 69°C(156.2°F); bp 270°C (518°F); strongly basic;soluble in water and organic solvents.
Uses
(-)-Lupinine is an alkaloid capable of counteracting ethanol anesthesia.
Health Hazard
This alkaloid is moderately toxic. The toxicaction, however, is lower than that of cytisine. Ingestion of high doses may producenausea, convulsions, and respiratory fail ure. The lethal dose in guinea pigs by theintraperitoneal route is 28 mg/kg..
References
Baumert., Ber., 14, 1150, 1321, 1880, 1882 (1881)
Baumert., ibid, 15,631,1951 (1882)
Schmidt, Berend., Arch. Pharm., 235,263 (1897)
Willstiitter, Fourneau., Ber., 35, 1914 (1902)
Karrer et al., Helv. Chirn. Acta, 11, 1062 (1928)
Clemo, Raper, J. Chern. Soc., 1927 (1929)
Winterfeldt, Cosel., Arch. Pharrn., 70, 278 (1940)
Sadykov, Spasokukotski., J. Gen. Chern. USSR, 13,830 (1943)
Sadykov., ibid, 19,143 (1949)
Zaboev., ibid, 18,194 (1948)
Ratusky, Sorm., Chern. Listy., 47, 1491 (1953)
(-)-LUPININE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | China | 19805 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21628 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29859 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | China | 8772 | 58 | Inquiry |
| TargetMol Chemicals Inc. | United States | 38630 | 58 | Inquiry | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | China | 33338 | 58 | Inquiry |
| Aladdin Scientific | United States | 52924 | 58 | Inquiry | |
| TargetMol Chemicals Inc. | +8613564774135 | United States | 19881 | 58 | Inquiry |
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