DIHYDROFOLIC ACID

CAS No.: 4033-27-6

Chemical Name:: DIHYDROFOLIC ACID

Synonyms: dihydrofolate;FAH2;DIHYDROFOLIC ACID;FolinicAcidEPImpurityGHCl;Levofolinate EP Impurity G;Folinic Acid EP Impurity G;7,8-Dihydrofolic acid (DHF);DIHYDROPTEROYL-L-GLUTAMIC ACID;Folic Acid 7,8-Dihydro Impurity;Calcium levoflonate EP impurity G

CBNumber:: CB4432012

Molecular Formula:: C19H21N7O6

Molecular Weight:: 443.41

MOL File:: 4033-27-6.mol

MSDS File:: SDS

Modify Date:: 2024/4/24 19:16:04

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DIHYDROFOLIC ACID Properties

Melting point	>160°C (dec.)
Density	1.69±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	0.1 M NaOH: 10 mg/mL, slightly hazy, orange
pka	pKa 1.38(H2O t=25 I=0.10) (Occasionally);3.84(H2O t=25 I=0.10) (Occasionally)
form	Solid
color	Light Beige to Beige
BRN	69017
Stability	Air Sensitive, Hygroscopic, Temperature Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

NFPA 704

	0
2		0

DIHYDROFOLIC ACID price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D7006	Dihydrofolic acid ≥90%	4033-27-6	10MG	₹11236.35	2022-06-14	Buy
Sigma-Aldrich(India)	D7006	Dihydrofolic acid ≥90%	4033-27-6	25MG	₹21141.23	2022-06-14	Buy
Sigma-Aldrich(India)	D7006	Dihydrofolic acid ≥90%	4033-27-6	100MG	₹43386.6	2022-06-14	Buy

Product number	Packaging	Price	Buy
D7006	10MG	₹11236.35	Buy
D7006	25MG	₹21141.23	Buy
D7006	100MG	₹43386.6	Buy

DIHYDROFOLIC ACID Chemical Properties,Uses,Production

General Description

Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.

Purification Methods

DHFA is best purified by suspending (1g mostly dissolved)) in ice-cold sodium ascorbate (300mL of 10% at pH 6.0, prepared by adjusting the pH of 30g of sodium ascorbate in 150mL of H2O by adding 1N NaOH dropwise using a gla

DIHYDROFOLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

5,10-DiforMyl-5,6,7,8-tetrahydro Folic Acid L-Tetrahydrofolic Acid

DIHYDROFOLIC ACID Suppliers

Global( 96)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	18192627656	China	1328	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	China	52861	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry

Supplier	Advantage
SynZeal Research Pvt Ltd	58
Pharma Affiliates	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

4033-27-6(DIHYDROFOLIC ACID)Related Search:

Glycine Vitamin B12 Folic acid 2-[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methyl-formyl-amino]benzoyl]aminopentanedioic acid Calcium levofolinate

Calcium N5-methyltetrahydrofolate 5,10-DiforMyl-5,6,7,8-tetrahydro Folic Acid 10-Formylfolic Acid Folinic Acid IMpurity E 2-Amino-7-(chloromethyl)pteridin-4(1H)-one

2,4,5-Triamino-6-hydroxypyrimidine sulfate (S)-N-[4-[[(2-AMino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid 6-hydroxymethylpterin Folic Acid Impurity C 5-Methyl Tetrahedropteroic Acid (Mixture of DiastereoMers)

folcysteine (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE

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FAH2 DIHYDROPTEROYL-L-GLUTAMIC ACID DIHYDROFOLIC ACID 2-[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid 7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2 N-[4-[[[(2-Amino-1,4,5,6-tetrahydro-4-oxopteridin)-6-yl]methyl]amino]benzoyl]-L-glutamic acid (S)-2-(4-(((2-aMino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)Methyl)aMino)benzaMido)pentanedioic acid 7,8-Dihydrofolic acid (DHF) Dihydrofolic acid 7,8-Dihydropteroyl-L-glutaMic acid N-[4-[[(2-aMino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-GlutaMic acid Folinic Acid Impurity G (7,8-Dihydrofolic Acid) 7,8-DIHYDROPTEROYL-L-GLUTAMIC ACID 2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid Folic Acid 7,8-Dihydro Impurity Levofolinate EP Impurity G L-Glutamic acid, N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- Impurity G of Calcium Levofolinate Folic acid impurity 2/Folinic Acid EP Impurity G/Dihydrofolic acid/7,8-Dihydrofolic Acid Folinic Acid EP Impurity G Folinic Acid EP Impurity G (7,8-Dihydrofolic Acid) dihydrofolate (4-(((2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid Calcium levoflonate EP impurity G FolinicAcidEPImpurityGHCl 4033-27-6 40033-27-6 C19H21N7O6 Cell Signaling Enzymes Application Index Biochemicals and Reagents BioChemical Cofactors Dihydrofolate reductase Enzymes, Inhibitors, and Substrates Oxidation-Reduction Substrate/Cofactor