1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Structure
CAS No.
75629-57-1
Chemical Name:
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE
Synonyms
CS-1229;Oncrasin 1;ZERO/008607;ZINC00439476;AKOS B014321;Oncrasin 1 >ASISCHEM N15726;ART-CHEM-BB B014321;CHEMBRDG-BB 5601604;1-(4-chlorobenzyl)indole-3-carbaldehyde
CBNumber:
CB4698434
Molecular Formula:
C16H12ClNO
Molecular Weight:
269.73
MOL File:
75629-57-1.mol
Modify Date:
2023/6/30 15:45:59

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Properties

Melting point 115.0 to 119.0 °C
Boiling point 465.5±30.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥20mg/mL
form powder
color off-white to light tan
Sensitive Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
WGK Germany  3
HS Code  2933.99.9000
HazardClass  IRRITANT
NFPA 704
0
2 0

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 496265 Oncrasin-1 - CAS 75629-57-1 - Calbiochem A cell-permeable indolecarboxaldehyde compound that selectively induces apoptosis in cells harboring mutant K-Ras both in vitro and in vivo. 75629-57-1 25MG ₹15830.01 2022-06-14 Buy
TCI Chemicals (India) O0450 Oncrasin 1 75629-57-1 10MG ₹8800 2022-05-26 Buy
TCI Chemicals (India) O0450 Oncrasin 1 75629-57-1 50MG ₹14500 2022-05-26 Buy
Product number Packaging Price Buy
496265 25MG ₹15830.01 Buy
O0450 10MG ₹8800 Buy
O0450 50MG ₹14500 Buy

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Chemical Properties,Uses,Production

Uses

Oncrasin 1 is a proapoptotic compound.

Biological Activity

Proapoptotic agent that induces abnormal nuclear aggregation of PKC ι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC 50 ≤ 3 μ M) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo .

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Suppliers

Global( 114)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 China 25014 65 Inquiry
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE AKOS B014321 CHEMBRDG-BB 5601604 ART-CHEM-BB B014321 ASISCHEM N15726 Oncrasin 1 1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxaldehyde 1-(4-chlorobenzyl)-1H-indole-3-carbaldehyde(SALTDATA: FREE) 1-[(4-chlorophenyl)methyl]-3-indolecarboxaldehyde ZERO/008607 ZINC00439476 1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde 1-(4-chlorobenzyl)indole-3-carbaldehyde 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde CS-1229 Oncrasin-1 - CAS 75629-57-1 - Calbiochem Oncrasin 1 > 1H-Indole-3-carboxaldehyde, 1-[(4-chlorophenyl)methyl]- 1-(4-Chlorobenzyl)-1H-indole-3-carboxaldehyde 75629-57-1 C16H12CINO Apoptosis Inducers