ALPHA-CORTOLONE

ALPHA-CORTOLONE Structure
CAS No.
516-42-7
Chemical Name:
ALPHA-CORTOLONE
Synonyms
CORTOLONE;α-Cortolone;α-Cortolone-d5;ALPHA-CORTOLONE;Alpha Cortolone D5;A-cortolone crystalline;5β-Pregnane-3α,17α,20α,21-tetrol-11-one;5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One;3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one;(20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one
CBNumber:
CB4729833
Molecular Formula:
C21H34O5
Molecular Weight:
366.49
MOL File:
516-42-7.mol
Modify Date:
2023/7/14 17:48:11

ALPHA-CORTOLONE Properties

Melting point 208-209°
alpha D25 +44° (c = 0.5 in ethanol); D28 +34.2° (ethanol)
Boiling point 564.1±50.0 °C(Predicted)
Density 1.248±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka 13.95±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

ALPHA-CORTOLONE Chemical Properties,Uses,Production

Uses

α-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

ALPHA-CORTOLONE Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-CORTOLONE Suppliers

Global( 17)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 9287 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723 China 9247 58 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8740 58 Inquiry
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054 China 9268 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 19921389125 19921389125 China 12065 58 Inquiry
Steraloids Inc. 401 848-5422 United States 2357 68 Inquiry
Research Plus, Inc. 800 341-2296 (U.S. and Canada) United States 3676 51 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
3-ALPHA,17-ALPHA,20-ALPHA,21-TETRAHYDROXY-5-BETA-PREGNAN-11-ONE A-cortolone crystalline CORTOLONE ALPHA-CORTOLONE 5-BETA-PREGNAN-3-ALPHA, 17,20-ALPHA, 21-TETROL-11-ONE 5BETA-PREGNAN-3ALPHA,17ALPHA,20ALPHA,21-TETROL-11-ONE (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one (20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one 3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one 5β-Pregnane-3α,17α,20α,21-tetrol-11-one α-Cortolone α-Cortolone-d5 Alpha Cortolone D5 5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One Pregnan-11-one, 3,17,20,21-tetrahydroxy-, (3α,5β,20S)- 516-42-7