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MURAMIC ACID

MURAMIC ACID Structure
CAS No.
1114-41-6
Chemical Name:
MURAMIC ACID
Synonyms
MURAMIC ACID;MuramicAcid~99%;(+)-MURAMIC ACID;MURAMIC ACID, (+)-;aldehydo-muramicaci;aldehydo-muramic acid;MURAMIC ACID, (+)-(RG);MURAMIC ACID USP/EP/BP;MURAMIC ACID HYDRATE 98%;Muramic acid hydrate,98%
CBNumber:
CB4783314
Molecular Formula:
C9H17NO7
Molecular Weight:
251.23
MOL File:
1114-41-6.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

MURAMIC ACID Properties

Melting point 140-150 °C (dec.)
Boiling point 592.0±50.0 °C(Predicted)
alpha D25 +103° (c = 0.26 in water) (Matsushima, Park); D22 +146° (6 minutes) +116° (31 hrs) (c = 0.57 in water) (Osawa, Jeanloz)
Density 1.448±0.06 g/cm3(Predicted)
Flash point 14℃
storage temp. -20°C
solubility Methanol (Slightly), Water (Slightly)
pka 3.18±0.10(Predicted)
form Solid
color White to Light Brown
Merck 13,6328
BRN 1713780
Stability Hygroscopic
CAS DataBase Reference 1114-41-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  1
3-10
HS Code  2932990090

MURAMIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M2503 Muramic acid ≥95% 1114-41-6 5MG ₹7858.95 2022-06-14 Buy
Sigma-Aldrich(India) M2503 Muramic acid ≥95% 1114-41-6 25MG ₹35018.88 2022-06-14 Buy
Product number Packaging Price Buy
M2503 5MG ₹7858.95 Buy
M2503 25MG ₹35018.88 Buy

MURAMIC ACID Chemical Properties,Uses,Production

Chemical Properties

White Solid

General Description

Muramic acid is a marker for Gram-positive bacteria.

Purification Methods

Muramic acid crystallises from H2O or aqueous EtOH as the monohydrate which loses H2O at 80o in vacuo over P2O5. It sometimes contains some NaCl. It has been purified by dissolving 3.2g in MeOH (75mL), filtering from some insoluble material, concentrating to ~10mL and refrigerating. The colourless crystals are washed with absolute MeOH. This process does not remove NaCl; to do so, the product is recrystallised from an equal weight of H2O to give a low recovery yield of very pure acid (0.12g). On paper chromatography 0.26_g give one ninhydrin positive spot after development with 75% phenol (RF 0.51) or with sec-BuOH/HCO2H/H2O (7:1:2) (RF 0.30). [Matsushima & Park Biochemical Preparations 10 109 1963, J Org Chem 27 3581 1962.] The acid has also been purified by dissolving 990mg in 50% aqueous EtOH (2mL), cooling, collecting the colourless needles on a sintered glass funnel and drying over P2O5 at 80o/0.1mm to give the anhydrous acid. [Lambert & Zilliken Chem Ber 93 2915 1960.] Alternatively the acid is dissolved in a small volume of H2O, neutralised to pH 7 with ion-exchange resin beads (IR4B in OH-form), filtered, evaporated and dried. The residue is recrystallised from 90% EtOH (v/v) and dried as above for 24hours. [Strange & Kent Biochem J 71 333 1959.] The N-acetyl derivative (NAMA, R-2-(acetylamino)-3-O -(1-carboxyethyl)-2-deoxy-D-glucose, R -2(2 -acetylamino-2-deoxy -D-glucose -3-yloxy)-propionic acid) [10597-89-4], M 292.3, has m ~125o (dec) and [] 20D +41.2o after 24hours (c 1.5, H2O), pKEst ~ 3.6. [Watanabe & Saito J Bacteriol 144 428 1980, Beilstein 4 IV 2029.]

MURAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3-O-[1-CARBOXYETHYL]-2-DEOXY-D-GLUCOSE (R)-2-AMINO-3-O-(1-CARBOXYETHYL)-2-DEOXY-D-GLUCOSE (+)-MURAMIC ACID MURAMIC ACID MURAMIC ACID, (+)- MURAMIC ACID HYDRATE 98% MuramicAcid~99% 2-amino-3-o-(1-carboxyethyl)-2 2-[3-amino-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoic acid 2-Amino-3-O-[(R)-1-carboxyethyl]-2-deoxy-D-glucose Muramic acid hydrate,98% MURAMIC ACID, (+)-(RG) ethyl 3-aMino-2-(o-tolyl)propanoate oxalate aldehydo-muramic acid Muramic acid,2-Amino-3-O-(1-carboxyethyl) -2-deoxy-D-glucose MURAMIC ACID USP/EP/BP aldehydo-muramicaci (2R)-2-[[(2S,3R,4R,5S,6R)-3-ammonio-2,5-dihydroxy-6-(hydroxymethyl)-4-oxanyl]oxy]propanoate -D-glucopyranosyl]-1,6-bis-O-(phenylmethyl)-&alpha (R)-N-Acetyl-4-O-[2-(acetylamino)-2-deoxy-&beta (R)-2-(((2R,3R,4R,5R)-2-Amino-4,5,6-trihydroxy-1-oxohexan-3-yl)oxy)propanoic acid 1114-41-6 C9H17NO7H2O C9H17NO7xH2O C9H17NO7 Monosaccharide BioChemical Biochemicals and Reagents Carbohydrates 13C & 2H Sugars aldehydes Carbohydrates & Derivatives Labeling and Diagnostics Reagents