1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE

CAS No.: 547756-93-4

Chemical Name:: 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE

Synonyms: JTE 013;1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea;1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE;N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide

CBNumber:: CB4838782

Molecular Formula:: C17H19Cl2N7O

Molecular Weight:: 408.28506

MOL File:: 547756-93-4.mol

Request For Quotation

1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Properties

storage temp.	Store at +4°C

1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Chemical Properties,Uses,Production

Biological Activity

Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P 2 (EDG-5). Inhibits S1P binding to human S1P 2 receptors with an IC 50 value of 17.6 nM. At concentrations up to 10 μ M, displays 4.2% inhibition of S1P 3 and does not antagonize S1P 1 . Enhances S1P-induced angiogenesis in vivo .

1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Suppliers

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Supplier	Advantage
InvivoChem	58
amyjetsci	58
BOC Sciences	65
InvivoChem	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BIOTREND Chemicals AG	62
Service Chemical Inc.	71
Tocris Bioscience	77
Shanghai Hao Biological Technology Co., Ltd.	58
Xiamen Huijia Biological Technology Co., Ltd.	58

547756-93-4(1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE)Related Search:

Semicarbazide 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE 6-HYDRAZINO-1,3,4-TRIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE

N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE JTE 013 1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea 547756-93-4 C17H19N7OCl2 Lysophospholipid receptor and related