2-Bromo-5-chloro-1,3-difluorobenzene
![2-Bromo-5-chloro-1,3-difluorobenzene Structure](CAS/GIF/883546-16-5.gif)
- CAS No.
- 883546-16-5
- Chemical Name:
- 2-Bromo-5-chloro-1,3-difluorobenzene
- Synonyms
- 4-Chloro-2,6-difluorobromobenzene;3,5-Difluoro-4-bromo-chlorobenzene;1-Bromo-4-chloro-2,6-difluorobenzene;4-Bromo-1-chloro-3,5-difluorobenzene;2-Bromo-5-chloro-1,3-difluorobenzene;Benzene, 2-broMo-5-chloro-1,3-difluoro-;2-Bromo-5-Chloro-1,3-Difluorobenzene,>98%;4-Bromo-1-chloro-3,5-difluorobenzene ISO 9001:2015 REACH;1-Bromo-4-chloro-2,6-difluorobenzene [4-Bromo-3,5-difluorochlorobenzen
- CBNumber:
- CB4971779
- Molecular Formula:
- C6H2BrClF2
- Molecular Weight:
- 227.43
- MOL File:
- 883546-16-5.mol
- Modify Date:
- 2024/2/19 14:08:00
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HazardClass | IRRITANT |
HS Code | 2903998090 |
2-Bromo-5-chloro-1,3-difluorobenzene Chemical Properties,Uses,Production
Synthesis
2-Bromo-5-chloro-1,3-difluorobenzene is synthesised using 4-bromo-3,5-difluoroaniline as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-bromo-3,5-difluoroaniline (25.0g, 117mmol), copper chloride (I) (23.1g, 230mmol) and copper chloride (II) (47.0g, 350mmol) in acetonitrile (150 mL) mixed solution in, it was added dropwise acetonitrile (50 mL) solution of isoamyl nitrite (49.0mL, 350mmol) at room temperature. After stirring for 4 hours at room temperature the mixture solution, poured into 2N hydrochloric acid (300mL), diethyl - ether (200m And extracted with L × 3). The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to obtain a crude product of a brown solid. By purifying this product by a silica gel column (hexane), 2-bromo-5-chloro-1,3-difluorobenzene as a yellow oil (21.4 g, yield: 81%) was obtained.
Uses
2-Bromo-5-chloro-1,3-difluorobenzene is an organic intermediate that can be used to prepare other heterocyclic compounds as materials for organic electroluminescent devices.
2-Bromo-5-chloro-1,3-difluorobenzene Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16220 | 58 | Inquiry |
Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | China | 1377 | 60 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12962 | 58 | Inquiry |
Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | China | 5791 | 58 | Inquiry |
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