Bizelesin

CAS No.: 129655-21-6

Chemical Name:: Bizelesin

Synonyms: U-77779;Bizelesin;NSC-615291;(8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe;1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea;N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea;Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-;1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea

CBNumber:: CB51016702

Molecular Formula:: C43H36Cl2N8O5

Molecular Weight:: 815.7

MOL File:: 129655-21-6.mol

Modify Date:: 2024/7/2 8:55:09

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Bizelesin Properties

Density	1.604±0.06 g/cm3(Predicted)
pka	10.06±0.40(Predicted)
form	Solid
color	Off-white to yellow

Bizelesin Chemical Properties,Uses,Production

Uses

As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both si ngle-strand lesions and double-strand DNA cross-links. liferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).

Bizelesin Preparation Products And Raw materials

Raw materials

Preparation Products

Bizelesin Suppliers

Global( 21)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266	China	4362	55	Inquiry
Xi'an Lechun Chemical Co., Ltd	029-15596886083 15596886083	China	3866	58	Inquiry
Elucigen bio	13501719342	China	4649	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24647	58	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6343	56	Inquiry
Hangzhou Yuhao Chemical Technology Co., Ltd	0571-82693216	China	9394	52	Inquiry
Toronto Research Chemicals	+1 (416) 665-9696	Canada	6088	71	Inquiry
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	China	94658	76	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Xi'an Lechun Chemical Co., Ltd	58
Elucigen bio	58
TargetMol Chemicals Inc.	58
Lanospharma Laboratories Co.,Ltd	56
Hangzhou Yuhao Chemical Technology Co., Ltd	52
Toronto Research Chemicals	71
J & K SCIENTIFIC LTD.	76

129655-21-6(Bizelesin)Related Search:

4-Methyl-5-aminoindole Bizelesin 5-AMINOINDOLE HYDROCHLORIDE 7-Hydroxyindole 3-Dimethylamino-2-methylpropyl chloride hydrochloride

5-ACETAMIDOINDOLE

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1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea NSC-615291 U-77779 (8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea Bizelesin 1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]- 129655-21-6 C43H36Cl2N8O5 Chiral Reagents Indole Derivatives Intermediates & Fine Chemicals Pharmaceuticals