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Sufentanil

Sufentanil Structure
CAS No.
56030-54-7
Chemical Name:
Sufentanil
Synonyms
R-30730;Sufentanyl;Sulfentanil;Sufentanil (CRM);Sufentanil-d3?HCl;Sufentanil-D5 solution;Rezvilutamide Impurity 37;SUFENTANIL (D5, 98%) 100 UG/ML IN METHANOL;N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide;N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl]-N-phenylpropionamide
CBNumber:
CB51105211
Molecular Formula:
C22H30N2O2S
Molecular Weight:
386.55
MOL File:
56030-54-7.mol
Modify Date:
2023/6/8 9:02:16

Sufentanil Properties

Melting point 103-104℃
Boiling point 493.1±40.0 °C(Predicted)
Density 1.20 g/cm3
Flash point 9℃
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in ethanol (96 per cent) and in methanol.
form A neat solid
pka 7.89±0.20(Predicted)
Water Solubility 76mg/L(25 ºC)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
Toxicity LD50 i.v. in mice: 18.7 mg/kg (Van Bever)
NFPA 704
0
4 0

Sufentanil Chemical Properties,Uses,Production

Description

Sufentanil is a narcotic analgesic with a greater potency and therapeutic ratio than its structural relative fentanyl. It appears to produce fewer cardiac effects and less respiratory depression than fentanyl, and thus is especially useful as an analgesic/anesthetic in open heart surgery.

Chemical Properties

White or almost white powder.

Uses

Opioid receptor agonist; analgesic.

Definition

ChEBI: An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid.

Sufentanil Preparation Products And Raw materials

N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl]-N-phenylpropionamide R-30730 Sulfentanil Sufentanyl N-[4-(Methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropionamide Sufentanil-D5 solution 1-[Phenyl[1-[2-(2-thienyl)ethyl]-4-(methoxymethyl)-4-piperidinyl]amino]-1-propanone N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide Sufentanil (CRM) Propanamide, N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl- Sufentanil-d3?HCl SUFENTANIL (D5, 98%) 100 UG/ML IN METHANOL Rezvilutamide Impurity 37 56030-54-7 C22H25D5N2O2S