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Ortataxel

Ortataxel Structure
CAS No.
186348-23-2
Chemical Name:
Ortataxel
Synonyms
IDN 5109;Ortataxel;Radalbuvir;BAY 59-8862;SB-T 101131;5β,20-epoxy-1,2α,4,7β,13α,14β-heptahydroxytax-11-en-9-one 1,14-carbonate-4,10-diacetate-2-benzoate-13-[(2R,3S)-3-(N-tert-butoxycarbonyl)-amino-2-hydroxy-5-methylhexanoate];Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (3aS,4R,7R,8aS,9S,10aR,12aS,12bR,13S,13aS)-7,12a-bis(acetyloxy)-13-(benzoyloxy)-3a,4,7,8,8a,9,10,10a,12,12a,12b,13-dodecahydro-9-hydroxy-5,8a,14,14-tetramethyl-2,8-dioxo-6,13a-methano-13aH-oxeto[2'',3'':5',6']benzo[1',2':4,5...;Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (3aS,4R,7R,8aS,9S,10aR,12aS,12bR,13S,13aS)-7,12a-bis(acetyloxy)-13-(benzoyloxy)-3a,4,7,8,8a,9,10,10a,12,12a,12b,13-dodecahyd ro-9-hydroxy-5,8a,14,14-tetramethyl-2,8-dioxo-6,13a-methano-13aH-oxeto[2'',3'':5',6']benzo[1',2':4,5]cyclodeca[1,2-d]-1,3-dioxol-4-yl ester, (2R,3S)-
CBNumber:
CB51216038
Molecular Formula:
C44H57NO17
Molecular Weight:
871.92
MOL File:
186348-23-2.mol
Modify Date:
2024/9/4 6:44:39
Request For Quotation

Ortataxel Properties

Boiling point 929.7±65.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
solubility Soluble in DMSO
pka 11.75±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H331
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501

Ortataxel Chemical Properties,Uses,Production

Definition

Ortataxel is a semisynthetic, second-generation taxane derivative with potential antineoplastic activity. Ortataxel binds to and stabilizes tubulin molecules, thereby interfering with the dynamics of microtubule assembly/disassembly. This results in the inhibition of cell division and cellular proliferation. As it represents a poor substrate for P-glycoprotein (P-gp), multi-drug resistance protein (MRP-1) and breast cancer resistance protein (BCRP) mediated efflux, ortataxel modulates multi-drug resistance mechanisms and may be useful for treating multi-drug resistant tumors that express Pgp, MRP-1 and BCRP.

Ortataxel Preparation Products And Raw materials

Raw materials

Preparation Products

Ortataxel Suppliers

Global( 14)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 CHINA 6550 58 Inquiry
Shanghai Lianmai Biological Engineering Co., Ltd. 13052188602 CHINA 6700 58 Inquiry
Shanghai Yanjin Biological Technology Co., Ltd. 021-65232515 CHINA 6899 58 Inquiry
Shanghai Ruichu Biotechnology Co., Ltd. 021-59145618 CHINA 6970 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
Supplier Advantage
ApexBio Technology 58
Shanghai Zeye Biotechnology Co., Ltd. 58
Shanghai Lianmai Biological Engineering Co., Ltd. 58
Shanghai Yanjin Biological Technology Co., Ltd. 58
Shanghai Ruichu Biotechnology Co., Ltd. 58
MedBioPharmaceutical Technology Inc 58

186348-23-2(Ortataxel)Related Search:

Paclitaxel BOC-L-BETA-HOMOLEUCINE (R)-(+)-Propylene carbonate 4-HYDROXYMETHYL-1,3-DIOXOLAN-2-ONE (2R,3S)-3-AMINO-2-HYDROXYHEXANOIC ACID
(S)-(-)-Propylene Carbonate BOC-L-BETA-HOMOALANINE ALLYL ESTER 1-Benzylglycerol-2,3-carbonate (methoxymethoxy)cyclododecane CHEMBRDG-BB 4012459
3-cis-Hexenyl methyl carbonate Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (3aS,4R,7R,8aS,9S,10aR,12aS,12bR,13S,13aS)-7,12a-bis(acetyloxy)-13-(benzoyloxy)-3a,4,7,8,8a,9,10,10a,12,12a,12b,13-dodecahyd ro-9-hydroxy-5,8a,14,14-tetramethyl-2,8-dioxo-6,13a-methano-13aH-oxeto[2'',3'':5',6']benzo[1',2':4,5]cyclodeca[1,2-d]-1,3-dioxol-4-yl ester, (2R,3S)- 3-[(T-BUTOXYCARBONYL)AMINO]-5-METHYLHEXANOICACID N-BOC-(2R,3S)-2-HYDROXY-3-AMINO-5-METHYLHEXANOIC ACID (S)-(-)-4-(METHOXYMETHYL)-1,3-DIOXOLAN-2-ONE
BOISAMBRENE FORTE
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Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (3aS,4R,7R,8aS,9S,10aR,12aS,12bR,13S,13aS)-7,12a-bis(acetyloxy)-13-(benzoyloxy)-3a,4,7,8,8a,9,10,10a,12,12a,12b,13-dodecahyd ro-9-hydroxy-5,8a,14,14-tetramethyl-2,8-dioxo-6,13a-methano-13aH-oxeto[2'',3'':5',6']benzo[1',2':4,5]cyclodeca[1,2-d]-1,3-dioxol-4-yl ester, (2R,3S)- Ortataxel BAY 59-8862 IDN 5109 SB-T 101131 Radalbuvir 5β,20-epoxy-1,2α,4,7β,13α,14β-heptahydroxytax-11-en-9-one 1,14-carbonate-4,10-diacetate-2-benzoate-13-[(2R,3S)-3-(N-tert-butoxycarbonyl)-amino-2-hydroxy-5-methylhexanoate] Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (3aS,4R,7R,8aS,9S,10aR,12aS,12bR,13S,13aS)-7,12a-bis(acetyloxy)-13-(benzoyloxy)-3a,4,7,8,8a,9,10,10a,12,12a,12b,13-dodecahydro-9-hydroxy-5,8a,14,14-tetramethyl-2,8-dioxo-6,13a-methano-13aH-oxeto[2'',3'':5',6']benzo[1',2':4,5... 186348-23-2 C44H57NO17