Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).
- CAS No.
- 26581-81-7
- Chemical Name:
- Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).
- Synonyms
- EM12;CID91585;Thalidomide Impurity 4;PHTHALIMIDINOGLUTARIMIDE;2-(1-Oxo-2-isoindolinyl)glutarimide;2-(2,6-dioxopiperidin-3-yl)phthalimidine;2-(2,6-Dioxopiperiden-3-yl) phthalimidine;Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).;2-(2,6-Dioxo-3-piperidinyl)isoindoline-1-one;3-(1-Oxoisoindolin-2-yl)-2,6-piperidinedione
- CBNumber:
- CB51251808
- Molecular Formula:
- C13H12N2O3
- Molecular Weight:
- 244.25
- MOL File:
- 26581-81-7.mol
- Modify Date:
- 2024/7/2 8:55:10
| Boiling point | 383.99°C (rough estimate) |
|---|---|
| Density | 1.2650 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | -20°C |
| solubility | DMF: 5 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 1 mg/ml |
| form | A crystalline solid |
| pka | 10.70±0.40(Predicted) |
| color | Off-white to gray |
| EPA Substance Registry System | 2-(1-Oxo-2-isoindolinyl)glutarimide (26581-81-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| NFPA 704 |
|
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). Chemical Properties,Uses,Production
General Description
White crystalline powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). is an example of an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). emits toxic fumes of nitrogen oxides.
Fire Hazard
Flash point data for Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). are not available; however, Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). is probably combustible.
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11927 | 58 | Inquiry |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | China | 6000 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | China | 42057 | 58 | Inquiry |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | China | 39997 | 58 | Inquiry |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | China | 63720 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 40857 | 58 | Inquiry |
| Shaoyuan Technology (Shanghai) Co., Ltd. | 021-50795510 4000665055 | China | 9276 | 58 | Inquiry |