Chinese english Japanese Germany Korea

CETRORELIX

CETRORELIX Structure
CAS No.
145672-81-7
Chemical Name:
CETRORELIX
Synonyms
Cetrorelix impurity;Ns 75a;D 20761;Ovurelix;Cetrotid;Sb 075 acetate;SB-075 ACETATE;NS-75A;Cetrorelix( x acetate);Cetrorelix acetate (SB-75);Cetrorelix Acetate,SB-075 acetate,NS-75A, >98%
CBNumber:
CB51478311
Molecular Formula:
C70H92ClN17O14.C2H4O2
Molecular Weight:
1491.11
MOL File:
145672-81-7.mol
Modify Date:
2024/7/2 8:55:10
Request For Quotation

CETRORELIX Properties

storage temp. -20°C
solubility methanol: soluble10%
form solid
color White to off-white
Water Solubility Soluble in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360F
Precautionary statements  P201-P280-P308+P313
Risk Statements  60-63
Safety Statements  22
WGK Germany  3

CETRORELIX price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C5249 Cetrorelix acetate ≥98% (HPLC) 145672-81-7 5MG ₹13044.13 2022-06-14 Buy
Sigma-Aldrich(India) C5249 Cetrorelix acetate ≥98% (HPLC) 145672-81-7 25MG ₹52263.1 2022-06-14 Buy
Product number Packaging Price Buy
C5249 5MG ₹13044.13 Buy
C5249 25MG ₹52263.1 Buy

CETRORELIX Chemical Properties,Uses,Production

Description

Cetrorelix is a synthetic peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with a Kd value of 0.2 nM for radioligand binding to murine LTK- cells expressing human GnRHR. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH (IC50 = 1.2 nM). In vivo, cetrorelix (60 μg per day) reduces tumor volume to 35% of control and decreases serum luteinizing hormone levels by 50% in a human epithelial ovarian cancer mouse xenograft model. Centrorelix (0.5 mg/kg) protects the primordial follicles (PMF) in mouse ovaries from damage induced by cyclophosphamide with 65% to 86% PMF survival compared to 46% PMF survival with a saline control. Formulations containing cetrorelix have been used to prevent ovulation during in vitro fertilization.

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: The acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

CETRORELIX Preparation Products And Raw materials

Raw materials

Preparation Products

CETRORELIX Suppliers

Global( 96)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Piramal Pharma Solutions +919892735994 Maharashtra, India 48 58 Inquiry
BDR Pharmaceuticals International Pvt Ltd +91-2240560560 +91-7718884418 Maharashtra, India 206 58 Inquiry
Apicore Pharmaceuticals Pvt Ltd +91-2662267177 +91-2662267166 Gujarat, India 181 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29899 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10311 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Cellmano Biotech Limited 0551-65326643 18156095617 China 999 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
Supplier Advantage
Piramal Pharma Solutions 58
BDR Pharmaceuticals International Pvt Ltd 58
Apicore Pharmaceuticals Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
career henan chemical co 58
Shenzhen Nexconn Pharmatechs Ltd 58
Chongqing Chemdad Co., Ltd 58
Cellmano Biotech Limited 58
Fuxin Pharmaceutical 58

145672-81-7(CETRORELIX)Related Search:

CETRORELIX CETRORELIX cetrorelix Acetylated cetrorelix NA CETRORELIX ACETATE (Sitraric Acetate)
Deamidated cetrorelix AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-NH2, ACETATE Cetrorelix trifluoroacetate Cetrorelix acetate Cetrorelix acetate
chevron_left

1of2

chevron_right
D 20761 D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt) Ns 75a Sb 075 acetate Cetrotid Ovurelix N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetic acid salt Cetrorelix Acetate,SB-075 acetate,NS-75A, >98% SB-075 ACETATE;NS-75A Cetrorelix( x acetate) Cetrorelix acetate (SB-75) Cetrorelix AcetateQ: What is Cetrorelix Acetate Q: What is the CAS Number of Cetrorelix Acetate Q: What is the storage condition of Cetrorelix Acetate Q: What are the applications of Cetrorelix Acetate Cetrorelix impurity SB-75,GnRH Receptor,Cetrorelix Acetate,Inhibitor,SB 75,Gonadotropin releasing hormone receptor,inhibit,SB75,GNRHR (S)-N-((R)-1-Amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-20-(4-chlorobenzyl)-2-(3-guanidinopropyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureid 145672-81-7 C70H92ClN17O14xC2H4O2 Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals