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[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Structure
CAS No.
170729-79-0
Chemical Name:
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
Synonyms
(2r-(2ar;Arepitam intermediate 2;Fosaprepitant Impurity 32;(S,R,S)-Enantiomer Aprepitant;Aprepitant M2 Metabolite 1-Epimer;Aprepitant M2 Metabolite (1S, 2R, 3S)-Isomer;[2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl];[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine;Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2R,3S)-;Morpholine,2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-[2R-[2a(S*),3a]]
CBNumber:
CB51570475
Molecular Formula:
C20H18F7NO2
Molecular Weight:
437.35
MOL File:
170729-79-0.mol
Modify Date:
2023/5/15 10:44:00

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Properties

Boiling point 387.9±42.0 °C(Predicted)
Density 1.37
solubility DMSO (Slightly), Methanol (Slightly)
form Thick Oil
pka 6.93±0.60(Predicted)
color Pale Yellow
CAS DataBase Reference 170729-79-0(CAS DataBase Reference)

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Preparation Products And Raw materials

Raw materials

Preparation Products

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Suppliers

Global( 45)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
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Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 China 5000 58 Inquiry
[2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl] [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine [2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)- Morpholine Morpholine,2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-[2R-[2a(S*),3a]] (2r-(2ar (S,R,S)-Enantiomer Aprepitant Fosaprepitant Impurity 32 Aprepitant M2 Metabolite (1S, 2R, 3S)-Isomer Arepitam intermediate 2 Aprepitant M2 Metabolite 1-Epimer Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2R,3S)- (2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride 170729-79-0 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals