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(-)-LEUKOTRIENE A4 METHYL ESTER

(-)-LEUKOTRIENE A4 METHYL ESTER Structure
CAS No.
73466-12-3
Chemical Name:
(-)-LEUKOTRIENE A4 METHYL ESTER
Synonyms
(-)-leukotriene A4;PWXYNAKNLZUYAL-WAQVJNLQSA-N;LEUKOTRIENE A4 METHYL ESTER;(-)-LEUKOTRIENE A4 METHYL ESTER;LTA4 (Leukotriene A4 methyl ester);5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER;LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE);2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-
CBNumber:
CB5184743
Molecular Formula:
C21H32O3
Molecular Weight:
332.48
MOL File:
73466-12-3.mol
Modify Date:
2023/6/28 8:28:16
Request For Quotation

(-)-LEUKOTRIENE A4 METHYL ESTER Properties

storage temp. −20°C
solubility Acetone: >50 mg/ml; DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: insoluble and unstable.
form triethylamine:hexane solution

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H225-H315-H319-H361-H336-H373-H304-H411
Precautionary statements  P201-P202-P210-P240-P241-P242-P243-P260-P264-P271-P273-P280-P301+P310-P321-P331-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P314-P362+P364-P332+P313-P337+P313-P370+P378-P391-P403+P233-P403+P235-P405-P501
Hazard Codes  F,Xn,N
Risk Statements  11-36/37/38-48/20-51/53-62-65-67
Safety Statements  9-16-29-33-36/37-61-62
RIDADR  UN 1208 3/PG 2
WGK Germany  2
NFPA 704
3
2 0

(-)-LEUKOTRIENE A4 METHYL ESTER Chemical Properties,Uses,Production

Description

Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

Uses

LTA4 (Leukotriene A4 methyl ester) is an unstable intermediate in the biosynthesis of LTB4 and LTC4.

(-)-LEUKOTRIENE A4 METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-LEUKOTRIENE A4 METHYL ESTER Suppliers

Global( 33)Suppliers
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Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Biomol Feinchemikalien GmbH 49-40-8532600 Germany 479 74 Inquiry
Wako Pure Chemical Industries, Ltd. +81 6 6203 3741 Japan 6828 80 Inquiry
Spectrum Info. Ltd. 380 44 573 23 97 Ukraine 2742 53 Inquiry
Interchim S.A. (33) 4 70 03 88 55 France 6307 76 Inquiry
R & D Systems 612 379 2956 United States 2195 82 Inquiry
AXXORA, LLC +41 (0) 61 926 8989 Switzerland 1104 80 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
Supplier Advantage
Alfa Chemistry 58
Aladdin Scientific 58
TargetMol Chemicals Inc. 58
Biomol Feinchemikalien GmbH 74
Wako Pure Chemical Industries, Ltd. 80
Spectrum Info. Ltd. 53
Interchim S.A. 76
R & D Systems 82
AXXORA, LLC 80
kemikalieimport 47

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(-)-LEUKOTRIENE A4 METHYL ESTER LEUKOTRIENE A4 METHYL ESTER (-)-leukotriene A4 LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE) LTA4 (Leukotriene A4 methyl ester) 5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER PWXYNAKNLZUYAL-WAQVJNLQSA-N 2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)- 73466-12-3 Biochemicals and Reagents BioChemical Unsaturated fatty acids and derivatives Esters Fatty Acids Methyl Esters Lipids