(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE

CAS No.: 151792-53-9

Chemical Name:: (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE

Synonyms: (6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE;(1R,4S)-2-Boc-3-oxo-2-azabicyclo[2.2.1]hept-5-ene;(1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one;tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate;(1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate;racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate*;2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate;2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)-;(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester

CBNumber:: CB52459670

Molecular Formula:: C11H15NO3

Molecular Weight:: 209.24

MOL File:: 151792-53-9.mol

MSDS File:: SDS

Modify Date:: 2022/8/26 12:24:16

Request For Quotation

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Properties

Melting point	85.0-86.5 °C
Boiling point	339.8±31.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	-2.32±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Chemical Properties,Uses,Production

Uses

(1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

(1S-cis)-4-Amino-2-cyclopentene-1-methanol (S)-4-((tert-butoxycarbonyl)amino)cyclopent-1-enecarboxylic acid

(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE Suppliers

Global( 41)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	CHINA	21149	58	Inquiry
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	China	6938	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58	Inquiry
Labnetwork lnc.	+86-27-50766799 +8618062016861	China	19994	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	+8618235132063	China	3725	58	Inquiry
SuZhou Medinoah Co.,LTD.	0512-0512-69561983 13914027025	China	3440	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai UCHEM Inc.	58
AFINE CHEMICALS LIMITED	58
Labnetwork lnc.	58
LEAPCHEM CO., LTD.	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	58
SuZhou Medinoah Co.,LTD.	58

151792-53-9((6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE)Related Search:

tert-butyl (3aS,6aR)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3a,4,6a-tetrahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 3-N-Boc-Cis-Tetrahydrofuran-3,4-Diamine tert-butyl (3aR,5s,6aS)-5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-methanol Carbamic acid, [(3S,4S)-4-aminotetrahydro-3-furanyl]-, 1,1-dimethylethyl ester

tert-butyl ((3S,4S)-4-aminotetrahydrofuran-3-yl)carbamate rel tert-butyl ((3R,4R)-4-hydroxytetrahydro-2H-pyran-3-yl)carbamate tert-Butyl 5-(hydroxymethyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate rel-(3r,4r)-3-(boc-amino)-5-fluoropiperidine (2S,4R)-4-hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

tert-butyl ((3R,4R)-4-aminotetrahydrofuran-3-yl)carbamate N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL tert-butyl (3S)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate tert-butyl (3R,4S)-3-amino-4-methylpyrrolidine-1-carboxylate tert-butyl (3R)-3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxyla

(R)-1-BOC-3-(Hydroxymethyl)piperazine tert-butyl (3aR,7aS)-6-oxohexahydropyrano[3,4-c]pyrrole-2(3H)-carboxylate tert-butyl (3aR,5s,6aS)-5-cyanohexahydrocyclopenta[c]-pyrrole-2(1H)-carboxylate

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(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE (1R,4S)-tert-butyl 3-oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylate 2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-oxo-,1,1-diMethylethyl ester, (1R,4S)- tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate racemic-(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate* (1R,?4S)?-3-?Oxo-2-?azabicyclo[2.2.1]?hept-?5-?ene-?2-?carboxylic acid 1,?1-?Dimethylethyl Ester (1R,4S)-(-)-2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]hept-5-en-3-one 2-Methyl-2-Propanyl (1R,4S)-3-Oxo-2-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxylate (1R,4S)-2-Boc-3-oxo-2-azabicyclo[2.2.1]hept-5-ene 151792-53-9